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KLF6 Knockout Cell Lines

Gene: KLF6

Official Full Name: KLF transcription factor 6provided by HGNC

Gene Summary: This gene encodes a member of the Kruppel-like family of transcription factors. The zinc finger protein is a transcriptional activator, and functions as a tumor suppressor. Multiple transcript variants encoding different isoforms have been found for this gene, some of which are implicated in carcinogenesis. [provided by RefSeq, May 2009]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO04257 KLF6 Knockout cell line (HeLa) Human KLF6 1:3~1:6 Negative Online Inquiry
KO04258 KLF6 Knockout cell line (HCT 116) Human KLF6 1:2~1:4 Negative Online Inquiry
KO04259 KLF6 Knockout cell line (HEK293) Human KLF6 1:3~1:6 Negative Online Inquiry
KO04260 KLF6 Knockout cell line (A549) Human KLF6 1:3~1:4 Negative Online Inquiry

Background

KLF6 Gene Knockout Cell Lines represent a crucial advancement in the field of molecular biology, specifically designed to facilitate the study of the KLF6 gene's role in cellular processes and its implications in various diseases. These cell lines are genetically modified to lack functional KLF6, a transcription factor known to be involved in key biological processes such as cell proliferation, differentiation, and apoptosis. By utilizing CRISPR/Cas9 technology, our KLF6 knockout cell lines provide a precise and reliable method to elucidate the gene's function and its involvement in oncogenesis and other pathologies.

The key function of these cell lines lies in their ability to mimic the loss-of-function mutations of the KLF6 gene, enabling researchers to investigate its contribution to tumorigenesis and disease progression. The knockout model allows for the dissection of KLF6-mediated pathways, offering insights into potential anti-cancer strategies and therapeutic targets. In clinical research settings, these models can aid in identifying biomarkers for cancer prognosis and treatment responses, enhancing translational research.

What sets our KLF6 Gene Knockout Cell Lines apart from alternatives is their comprehensive validation process, ensuring consistent performance and reproducibility. Each cell line is extensively characterized to confirm successful gene editing and analyze downstream effects on cell behavior. This critical quality makes them ideal tools for researchers aiming to generate robust and generalizable data.

Researchers and clinicians alike will find great value in our KLF6 knockout cell lines as they provide an indispensable resource for uncovering the intricacies of gene function and disease mechanisms. With our commitment to delivering high-quality biological products backed by rigorous scientific expertise, we empower the scientific community to advance discoveries that translate into clinical innovations, furthering our mission of enhancing human health through groundbreaking research.

Please note that all services are for research use only. Not intended for any clinical use.

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