Gene: KLF3
Official Full Name: KLF transcription factor 3provided by HGNC
Gene Summary: Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO22766 | KLF3 Knockout cell line (HeLa) | Human | KLF3 | 1:3~1:6 | Negative | Online Inquiry |
KO22767 | KLF3 Knockout cell line (HCT 116) | Human | KLF3 | 1:2~1:4 | Negative | Online Inquiry |
KO22768 | KLF3 Knockout cell line (HEK293) | Human | KLF3 | 1:3~1:6 | Negative | Online Inquiry |
KO22769 | KLF3 Knockout cell line (A549) | Human | KLF3 | 1:3~1:4 | Negative | Online Inquiry |
KLF3 Gene Knockout Cell Lines are genetically modified cell lines in which the Krüppel-like Factor 3 (KLF3) gene has been deliberately disrupted or "knocked out," enabling researchers to study the effects of loss of function in a controlled laboratory setting. KLF3 is a transcription factor known to play a crucial role in various cellular processes, including proliferation, differentiation, and metabolism. By creating specific knockout models, researchers can elucidate the gene's biological functions and its implications in disease states, such as metabolic disorders and certain cancers.
These cell lines are indispensable for understanding KLF3-related pathways and have applications in both basic and applied research. They provide a platform for high-throughput screening of drugs, functional assays, and gene expression studies, allowing for a detailed investigation of molecular mechanisms that underlie various physiological and pathological phenomena. Furthermore, by knocking out KLF3, researchers can explore compensatory mechanisms and identify potential therapeutic targets, making these models critical in advancing the fields of molecular biology and therapeutic development.
One significant advantage of KLF3 Gene Knockout Cell Lines is their ability to yield reproducible and consistent results that might not be feasible with transient silencing techniques or chemical inhibitors. This stability enhances the validity of experimental findings and allows for long-term studies. The precision of these models also exceeds that of other genetic manipulations, such as overexpression systems or knockout via CRISPR/Cas9, due to the established genetic background of the cell lines utilized.
For researchers and clinicians focused on gene regulation and its impact on various diseases, KLF3 Gene Knockout Cell Lines represent a unique opportunity to dissect complex biological processes. Their development provides a more profound understanding of genetic contributions to health and disease, promoting the potential for novel intervention strategies.
At our company, we pride ourselves on being at the forefront of genetic engineering technologies and cell line development, offering reliable, high-quality biological products tailored to meet the needs of the research community. Our expertise ensures that every product is developed with rigorous quality control, propelling discoveries in genomics and therapeutic applications.
Please note that all services are for research use only. Not intended for any clinical use.
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