Home / KLC4 Knockout Cell Lines

KLC4 Knockout Cell Lines

Gene: KLC4

Official Full Name: kinesin light chain 4provided by HGNC

Gene Summary: Predicted to enable kinesin binding activity. Predicted to be involved in microtubule-based movement. Predicted to be located in microtubule. Predicted to be part of kinesin complex. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO23884 KLC4 Knockout cell line (HeLa) Human KLC4 1:3~1:6 Negative Online Inquiry
KO23885 KLC4 Knockout cell line (HCT 116) Human KLC4 1:2~1:4 Negative Online Inquiry
KO23886 KLC4 Knockout cell line (HEK293) Human KLC4 1:3~1:6 Negative Online Inquiry
KO23887 KLC4 Knockout cell line (A549) Human KLC4 1:3~1:4 Negative Online Inquiry

Background

KLC4 Gene Knockout Cell Lines are meticulously engineered cellular models that enable researchers to investigate the role of the KLC4 gene in various biological processes. These cell lines are generated using advanced CRISPR/Cas9 gene-editing technology, allowing for the targeted disruption of the KLC4 gene. This precise knockout facilitates the assessment of the gene's function in cellular pathways, potentially affecting cellular transport mechanisms and signaling pathways.

The primary mechanism of KLC4 gene knockout involves the introduction of specific mutations that disrupt the normal transcription of the KLC4 protein, which is a crucial component of the kinesin family responsible for intracellular transport. By eliminating KLC4 expression, researchers can study the consequences of its absence on cellular dynamics, such as the degradation of cargo, cellular motility, and neuron development. These insights can significantly enhance our understanding of related disorders, including neurodegenerative diseases, where transport dysregulation plays a pivotal role.

The scientific importance of KLC4 Gene Knockout Cell Lines extends into both research and clinical settings. They serve as indispensable tools for drug discovery, helping to identify potential therapeutic interventions targeting transport mechanisms. In research, these cell lines offer a robust platform for elucidating the molecular pathways associated with KLC4 and how alterations may contribute to pathological states.

Advantages of using KLC4 Gene Knockout Cell Lines over alternative methods, such as transient knockdown techniques, include the stability of the knockout and the reproducibility of results. This stability allows for prolonged studies that yield insights over time, which are critical for comprehensive biological assessments. Furthermore, these cell lines are readily amenable to high-throughput screening, making them ideal for large-scale experimental setups.

Ultimately, the value of KLC4 Gene Knockout Cell Lines lies in their ability to provide a reliable and sophisticated model system that enhances the research capabilities of laboratories. By choosing our KLC4 Gene Knockout Cell Lines, researchers and clinicians gain access to a well-validated product backed by rigorous testing and a commitment to advancing scientific discovery. Our company leverages years of expertise in genetic engineering and cell line development, ensuring our offerings lead the way in innovative biological research tools.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.