Gene: KLC2
Official Full Name: kinesin light chain 2provided by HGNC
Gene Summary: The protein encoded by this gene is a light chain of kinesin, a molecular motor responsible for moving vesicles and organelles along microtubules. Defects in this gene are a cause of spastic paraplegia, optic atrophy, and neuropathy (SPOAN) syndrome. [provided by RefSeq, Mar 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO16695 | KLC2 Knockout cell line (HeLa) | Human | KLC2 | 1:3~1:6 | Negative | Online Inquiry |
KO16696 | KLC2 Knockout cell line (HCT 116) | Human | KLC2 | 1:2~1:4 | Negative | Online Inquiry |
KO16697 | KLC2 Knockout cell line (HEK293) | Human | KLC2 | 1:3~1:6 | Negative | Online Inquiry |
KLC2 Gene Knockout Cell Lines are genetically engineered cell lines in which the KLC2 gene has been selectively disrupted, allowing for the study of the gene's function and its role in cellular processes. KLC2, short for kinesin light chain 2, is critical for intracellular transport mediated by kinesin motor proteins. The knockout of this gene provides a valuable model for investigating the mechanistic contributions of KLC2 in vital biological processes such as neuronal signaling, cell division, and intracellular trafficking.
These cell lines function by utilizing CRISPR-Cas9 technology to create precise gene deletions, which enables researchers to explore the consequences of KLC2 loss at both cellular and molecular levels. By silencing this gene, scientists can observe alterations in cellular behaviors, protein interactions, and pathways involved in essential physiological processes. This opens avenues for understanding various pathological conditions, including neurodegenerative diseases and cancer, where kinesin function is often disrupted.
The scientific importance of KLC2 Gene Knockout Cell Lines lies in their broad applications in research and clinical settings. They serve as powerful tools for drug screening, functional assays, and the exploration of gene therapy approaches. Their utility in dissecting complex cellular mechanisms dramatically enhances our understanding of disease models and therapeutic targets.
What sets our KLC2 Gene Knockout Cell Lines apart from alternatives on the market is the precision of our genetic knockout methodology combined with rigorous validation processes. Each line is validated for consistent gene disruption and characterized for off-target effects, ensuring reliability and reproducibility in experimental outcomes.
For researchers and clinicians, these cell lines represent a pivotal resource that can accelerate the pace of discovery in molecular biology and translational medicine. By providing high-fidelity models that reflect gene knockout impacts, they facilitate innovative research approaches and the development of effective interventions.
Our company specializes in providing high-quality biological products backed by extensive expertise in cellular biology and genetics. We are committed to supporting your research endeavors with premier tools that meet and exceed the demands of the scientific community. Explore the potential of KLC2 Gene Knockout Cell Lines and leverage our commitment to excellence in your next project.
Please note that all services are for research use only. Not intended for any clinical use.
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