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KIFBP Knockout Cell Lines

Gene: KIFBP

Official Full Name: kinesin family binding proteinprovided by HGNC

Gene Summary: This gene encodes a kinesin family member 1 binding protein that is characterized by two tetratrico peptide repeats. The encoded protein localizes to the mitochondria and may be involved in regulating transport of the mitochondria. Mutations in this gene are associated with Goldberg-Shprintzen megacolon syndrome. [provided by RefSeq, Mar 2010]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO28298 KIFBP Knockout cell line (HeLa) Human KIFBP 1:3~1:6 Negative Online Inquiry
KO28299 KIFBP Knockout cell line (HCT 116) Human KIFBP 1:2~1:4 Negative Online Inquiry
KO28300 KIFBP Knockout cell line (HEK293) Human KIFBP 1:3~1:6 Negative Online Inquiry
KO28301 KIFBP Knockout cell line (A549) Human KIFBP 1:3~1:4 Negative Online Inquiry

Background

KIFBP Gene Knockout Cell Lines are specialized cellular models engineered to possess deletions in the kinesin family member 3B (KIFBP) gene. This product facilitates the study of KIFBP's role in various cellular processes, including cell division and intracellular transport, which are vital for understanding disease mechanisms related to cancer and neurodegenerative disorders. These knockout cell lines are created using advanced CRISPR-Cas9 technology, which allows for precise editing of the genomic sequence, thereby ensuring a reliable and reproducible model for researchers.

The key function of KIFBP is to act as a motor protein involved in the transport of numerous cellular components along microtubules. By disrupting the KIFBP gene, these knockout cell lines permit researchers to investigate the consequences of impaired intracellular transport and the resulting cellular dysregulation. This understanding is crucial for deciphering the roles that KIFBP may play in pathologies such as Alzheimer's disease and various tumor formations.

From a scientific standpoint, KIFBP Gene Knockout Cell Lines are invaluable in translational research and drug discovery. They enable the identification of novel therapeutic targets and the assessment of treatment efficacy in a genetically relevant context. In comparison to conventional cell lines, which may express functioning KIFBP, these knockout models provide a clear edge in elucidating the gene's specific contributions to cellular homeostasis and pathology.

The unique selling points of KIFBP Gene Knockout Cell Lines include their high specificity, reproducibility, and the ability to facilitate findings that might otherwise be obscured in wild-type settings. Their streamlined integration into existing research workflows positions them as an essential tool for researchers and clinicians alike.

Our company is dedicated to delivering high-quality genetic products, backed by a team of experts in molecular biology and genetics, ensuring that you have the resources necessary to advance your research and achieve scientific breakthroughs.

Please note that all services are for research use only. Not intended for any clinical use.

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