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KIF24 Knockout Cell Lines

Gene: KIF24

Official Full Name: kinesin family member 24provided by HGNC

Gene Summary: This gene encodes a member of the kinesin superfamily of microtubule-based motor proteins which are involved in the intracellular transport of membranous organelles, protein complexes, and mRNAs. They also play critical roles in mitosis, morphogenesis, and signal transduction. The encoded protein contains an N-terminal sterile alpha motif (SAM) domain and an ATP-binding kinesin motor domain. It binds centriolar coiled coil protein 110 and centrosomal protein 97 and localizes to the mother centriole to regulate ciliogenesis by controlling microtubule polymerization. [provided by RefSeq, Mar 2017]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO16717 KIF24 Knockout cell line (HeLa) Human KIF24 1:3~1:6 Negative Online Inquiry
KO16718 KIF24 Knockout cell line (HCT 116) Human KIF24 1:2~1:4 Negative Online Inquiry
KO16719 KIF24 Knockout cell line (HEK293) Human KIF24 1:3~1:6 Negative Online Inquiry
KO16720 KIF24 Knockout cell line (A549) Human KIF24 1:3~1:4 Negative Online Inquiry

Background

KIF24 Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to study the function of the KIF24 gene, which encodes a kinesin family protein implicated in cellular processes such as cilia assembly and mitotic spindle organization. By knocking out this gene, researchers can create a platform to unravel the physiological and pathological roles of KIF24, providing insights into its involvement in cellular dynamics and potential connections to diseases like cancer and ciliopathies.

The key function of the KIF24 Gene Knockout Cell Lines lies in their ability to enable the investigation of KIF24’s mechanistic pathways. Researchers can observe changes in cellular behavior, including alterations in cilia length, movement, and the dynamics of the microtubule cytoskeleton. This allows for a more nuanced understanding of how KIF24 contributes to cell division and differentiation, which are central to both normal development and disease progression.

From a scientific standpoint, these cell lines hold immense value in both research and clinical settings. They can be utilized in high-throughput screening assays to identify novel drugs that target KIF24-related pathways, potentially leading to therapeutic interventions for diseases where KIF24 plays a critical role. Furthermore, elucidating the function of KIF24 can aid in the development of biomarkers for disease states.

What sets our KIF24 Gene Knockout Cell Lines apart from alternatives is their superior reliability and reproducibility, achieved through advanced CRISPR-Cas9 gene editing technology. This ensures that researchers receive cell lines with consistent knockout efficiency, enabling a high degree of confidence in experimental outcomes.

For researchers and clinicians alike, the acquisition of KIF24 Gene Knockout Cell Lines cultivates an opportunity to explore uncharted areas in cellular biology, potentially transforming our approach to understanding complex biological systems. Our company's commitment to scientific innovation and excellence in producing high-quality genetic tools uniquely positions us as a leading supplier in the field, empowering researchers to push the boundaries of their investigations into gene function and regulation.

Please note that all services are for research use only. Not intended for any clinical use.

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