Gene: KIF22
Official Full Name: kinesin family member 22provided by HGNC
Gene Summary: The protein encoded by this gene is a member of the kinesin-like protein family. The family members are microtubule-dependent molecular motors that transport organelles within cells and move chromosomes during cell division. The C-terminal half of this protein has been shown to bind DNA. Studies with the Xenopus homolog suggests its essential role in metaphase chromosome alignment and maintenance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO02802 | KIF22 Knockout cell line (HeLa) | Human | KIF22 | 1:3~1:6 | Negative | Online Inquiry |
KO02803 | KIF22 Knockout cell line (HCT 116) | Human | KIF22 | 1:2~1:4 | Negative | Online Inquiry |
KO02804 | KIF22 Knockout cell line (HEK293) | Human | KIF22 | 1:3~1:6 | Negative | Online Inquiry |
KO02805 | KIF22 Knockout cell line (A549) | Human | KIF22 | 1:3~1:4 | Negative | Online Inquiry |
KIF22 Gene Knockout Cell Lines represent a significant advancement in cellular research, providing a valuable tool for understanding the function of the KIF22 gene in various biological contexts. KIF22 is a member of the kinesin family of motor proteins, which play critical roles in intracellular transport, cell division, and development. By creating knockout cell lines, researchers can effectively silence the expression of the KIF22 gene, enabling the study of its specific contributions to cellular processes and disease mechanisms.
These cell lines operate through targeted genome editing techniques, such as CRISPR-Cas9, to disrupt the KIF22 gene. This disruption allows for the investigation of phenotypic changes and cellular behaviors associated with the loss of KIF22 function, facilitating insights into its role in diseases such as cancer and neurodegenerative disorders. The ability to manipulate gene expression in a controlled manner makes KIF22 Gene Knockout Cell Lines an invaluable resource in both fundamental and applied research.
The scientific importance of these cell lines extends to their application in drug discovery and therapeutic development, whereby understanding the pathways influenced by KIF22 could lead to novel treatment strategies. Compared to alternative models, such as overexpression systems or wild-type cell lines, knockout models offer a clearer picture of gene loss effects and a more comprehensive understanding of the gene's role in specific contexts.
For researchers and clinicians, the KIF22 Gene Knockout Cell Lines provide a dramatically streamlined approach to studying gene function and associated molecular pathways, significantly enhancing the quality and speed of research outcomes. Our commitment to genomic innovation and mastery of cutting-edge editing technologies positions us at the forefront of developing high-quality biological products. By choosing our KIF22 Gene Knockout Cell Lines, you are equipping your lab with a transformative tool that will drive new discoveries and advancements in the field of molecular biology.
Please note that all services are for research use only. Not intended for any clinical use.
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