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KIF13B Knockout Cell Lines

Gene: KIF13B

Official Full Name: kinesin family member 13Bprovided by HGNC

Gene Summary: Enables 14-3-3 protein binding activity and protein kinase binding activity. Involved in regulation of axonogenesis. Located in axon and cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO29508 KIF13B Knockout cell line (HeLa) Human KIF13B 1:3~1:6 Negative Online Inquiry
KO29509 KIF13B Knockout cell line (HCT 116) Human KIF13B 1:2~1:4 Negative Online Inquiry
KO29510 KIF13B Knockout cell line (HEK293) Human KIF13B 1:3~1:6 Negative Online Inquiry
KO29511 KIF13B Knockout cell line (A549) Human KIF13B 1:3~1:4 Negative Online Inquiry

Background

KIF13B Gene Knockout Cell Lines are innovative biological products designed to facilitate the functional analysis of the KIF13B gene, which encodes a member of the kinesin family of motor proteins. Kinesins are crucial for intracellular transport processes, and KIF13B is known to play significant roles in endosomal trafficking and cellular signaling pathways. These knockout cell lines are engineered to specifically disrupt the KIF13B gene, enabling researchers to study the consequences of its absence on cellular functions, morphology, and signaling cascades.

The primary function of KIF13B Gene Knockout Cell Lines is to allow scientists to elucidate the biological mechanisms through which the KIF13B protein operates. By knocking out this gene, researchers can observe resultant phenotypic changes and assess the impact on vital cellular processes, such as vesicle transport, endocytosis, and cell division. This mechanistic insight is invaluable for understanding diseases where KIF13B is implicated, such as certain cancers and neurological disorders.

The scientific importance of these knockout cell lines lies in their diverse applications in both fundamental and applied research. They enable the identification of novel therapeutic targets, the exploration of gene function, and the assessment of gene-gene interactions, thus providing a robust platform for drug discovery and development. Additionally, they can offer significant insights for clinical research concerning the efficacy of novel treatments that manipulate intracellular transport pathways.

Compared to alternatives, KIF13B Gene Knockout Cell Lines provide a more precise and controlled experimental environment. Many conventional methods for gene silencing can result in off-target effects, compromising data integrity. In contrast, our knockout lines specifically and reliably eliminate KIF13B expression, ensuring that observed effects are directly attributable to the gene's loss.

For researchers and clinicians, the value of these cell lines extends beyond mere experimental utility. They represent a pivotal tool for advancing our understanding of cellular dynamics, ultimately contributing to improved therapeutic strategies. Our commitment to quality and innovation is underscored by our team of experts in genetic manipulation and cell line development, providing users with reliable products that support cutting-edge biological research.

Please note that all services are for research use only. Not intended for any clinical use.

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