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KIAA1586 Knockout Cell Lines

Gene: KIAA1586

Official Full Name: KIAA1586provided by HGNC

Gene Summary: Enables SUMO ligase activity. Involved in protein sumoylation. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO16756 KIAA1586 Knockout cell line (HeLa) Human KIAA1586 1:3~1:6 Negative Online Inquiry
KO16757 KIAA1586 Knockout cell line (HCT 116) Human KIAA1586 1:2~1:4 Negative Online Inquiry
KO16758 KIAA1586 Knockout cell line (HEK293) Human KIAA1586 1:3~1:6 Negative Online Inquiry
KO16759 KIAA1586 Knockout cell line (A549) Human KIAA1586 1:3~1:4 Negative Online Inquiry

Background

KIAA1586 Gene Knockout Cell Lines are genetically engineered cells specifically designed to facilitate the study of the KIAA1586 gene's function by nullifying its expression. These cell lines provide researchers with a powerful tool for investigating the biological roles of KIAA1586, which has been implicated in various cellular processes, including cell signaling, proliferation, and differentiation. By utilizing CRISPR/Cas9 technology or other gene-editing methods, KIAA1586 is disrupted in these cell lines, allowing for comparative studies with wild-type control cells to discern the gene’s impact on cell function and pathology.

The primary mechanism of action involves the targeted deletion of the KIAA1586 gene, resulting in a lack of corresponding protein synthesis. This knockout effect allows researchers to elucidate the gene's contributions to metabolic pathways, disease states, or response mechanisms in vitro. The KIAA1586 cell lines serve as a crucial resource for uncovering potential therapeutic targets and understanding disease mechanisms, particularly in cancer and neurodevelopmental disorders.

By providing a specific and reliable model system for gene function analysis, the KIAA1586 Gene Knockout Cell Lines stand out among typical cell culture models due to their suitability for high-throughput screening and drug discovery applications. Their unique attributes yield advantages such as reducing confounding genetic variability and enhancing reproducibility in experimental results. This makes them an invaluable asset for both basic and translational research.

Researchers and clinicians will find these cell lines indispensable for advancing their work in gene function and therapeutic development, as they offer clear insights into the effects of KIAA1586 manipulation. Moreover, our company prides itself on its unwavering commitment to quality and innovation in the development of biological products. With extensive expertise in genetic engineering, we ensure that our KIAA1586 Gene Knockout Cell Lines deliver robust, reproducible results that meet the evolving needs of the scientific community.

Please note that all services are for research use only. Not intended for any clinical use.

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