Gene: KIAA1143
Official Full Name: KIAA1143provided by HGNC
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO16780 | KIAA1143 Knockout cell line (HeLa) | Human | KIAA1143 | 1:3~1:6 | Negative | Online Inquiry |
KO16781 | KIAA1143 Knockout cell line (HCT 116) | Human | KIAA1143 | 1:2~1:4 | Negative | Online Inquiry |
KO16782 | KIAA1143 Knockout cell line (HEK293) | Human | KIAA1143 | 1:3~1:6 | Negative | Online Inquiry |
KO16783 | KIAA1143 Knockout cell line (A549) | Human | KIAA1143 | 1:3~1:4 | Negative | Online Inquiry |
KIAA1143 Gene Knockout Cell Lines represent a groundbreaking tool for researchers studying gene function and associated biological pathways. These engineered cell lines have undergone CRISPR/Cas9-mediated gene editing to create a complete deletion of the KIAA1143 gene, allowing scientists to directly assess the impact of its absence on various cellular processes. By utilizing these knockout cell lines, researchers can investigate gene interactions, signaling pathways, and cellular responses, substantially enhancing our understanding of KIAA1143’s role in health and disease.
The core mechanism of action of KIAA1143 Gene Knockout Cell Lines involves the precise editing of the genome to create a loss-of-function model. This approach is instrumental in elucidating the gene’s contribution to complex traits, identifying downstream effects on gene expression, protein levels, and cellular morphology. The knockout model can enable the establishment of causal links between KIAA1143 and various physiological or pathological states, making it an invaluable asset in both basic and translational research contexts.
In terms of scientific importance, KIAA1143 has been implicated in processes such as cell proliferation, apoptosis, and possibly tumorigenesis. The availability of these knockout cell lines provides a platform for investigating potential therapeutic targets or biomarkers in oncology and other diseases. In clinical settings, findings derived from studies using these cell lines may contribute to the development of novel treatment strategies that specifically modulate the function of KIAA1143.
Advantages of the KIAA1143 Gene Knockout Cell Lines include their high specificity and reproducibility compared to alternative models, such as siRNA-mediated knockdown, which may produce incomplete or transient effects. Furthermore, these cell lines are readily available, allowing researchers to bypass lengthy generation processes typical of other genetic models.
Investing in KIAA1143 Gene Knockout Cell Lines empowers researchers and clinicians with the tools necessary to advance their studies into the gene's biological significance. This facilitates a deeper understanding of cellular mechanisms that could lead to innovative solutions in biomedical science. Our company specializes in the production and characterization of genetic models and is committed to supporting the scientific community with high-quality, reliable products that bolster research endeavors.
Please note that all services are for research use only. Not intended for any clinical use.
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