Gene: KHDRBS1
Official Full Name: KH RNA binding domain containing, signal transduction associated 1provided by HGNC
Gene Summary: This gene encodes a member of the K homology domain-containing, RNA-binding, signal transduction-associated protein family. The encoded protein appears to have many functions and may be involved in a variety of cellular processes, including alternative splicing, cell cycle regulation, RNA 3'-end formation, tumorigenesis, and regulation of human immunodeficiency virus gene expression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO00484 | KHDRBS1 knockout cell line (HeLa) | Human | KHDRBS1 | 1:3~1:6 | Negative | Online Inquiry |
KO02660 | KHDRBS1 Knockout cell line (HCT 116) | Human | KHDRBS1 | 1:2~1:4 | Negative | Online Inquiry |
KO02661 | KHDRBS1 Knockout cell line (HEK293) | Human | KHDRBS1 | 1:3~1:6 | Negative | Online Inquiry |
KO02662 | KHDRBS1 Knockout cell line (A549) | Human | KHDRBS1 | 1:3~1:4 | Negative | Online Inquiry |
KHDRBS1 Gene Knockout Cell Lines are genetically engineered cell lines designed to specifically knock out the KHDRBS1 gene, which encodes a protein that plays a crucial role in post-transcriptional regulation of gene expression. By utilizing CRISPR/Cas9 technology, researchers can induce targeted deletions within the KHDRBS1 gene, enabling comprehensive analysis of the gene's biological functions and its involvement in various cellular processes.
The primary function of KHDRBS1, also known as Sam68, involves regulating RNA splicing, stabilization, and transport, significantly influencing cellular responses to stress and differentiation. The knockout of this gene allows scientists to systematically evaluate the phenotypic and molecular changes resulting from its absence, offering valuable insights into its role in diseases such as cancer and neurodegenerative disorders. These models facilitate innovative exploration of potential therapeutic targets and advances in gene therapy approaches.
In research and clinical settings, KHDRBS1 Gene Knockout Cell Lines serve as pivotal tools for elucidating gene function and interactions, particularly in pathways related to RNA metabolism and cellular signaling. Compared to traditional knockout models, these cell lines provide a more efficient, reliable, and scalable solution for understanding the intricate roles of KHDRBS1, enabling higher throughput and reproducibility in experimental designs.
The advantage of using KHDRBS1 Gene Knockout Cell Lines lies not only in their precision and specificity but also in their relevance to ongoing studies exploring post-transcriptional regulation in human health and disease. For researchers and clinicians alike, these cell lines represent an invaluable resource, yielding deeper biological insights and advancing the field of molecular biology.
With a commitment to innovation and quality, our company is dedicated to providing researchers with cutting-edge genetic tools, ensuring reliability and excellence in every product we offer. Our expertise in developing advanced genetic models makes us a trusted partner in facilitating research that drives discovery and therapeutic breakthroughs.
Please note that all services are for research use only. Not intended for any clinical use.
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