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KANK2 Knockout Cell Lines

Gene: KANK2

Official Full Name: KN motif and ankyrin repeat domains 2provided by HGNC

Gene Summary: This gene encodes a member of the KN motif and ankyrin repeat domains (KANK) family of proteins, which play a role in cytoskeletal formation by regulating actin polymerization. The encoded protein functions in the sequestration of steroid receptor coactivators and possibly other proteins. Mutations in this gene are associated with impaired kidney podocyte function and nephrotic syndrome, and keratoderma and woolly hair. [provided by RefSeq, Jul 2016]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO28569 KANK2 Knockout cell line (HeLa) Human KANK2 1:3~1:6 Negative Online Inquiry
KO28570 KANK2 Knockout cell line (HCT 116) Human KANK2 1:2~1:4 Negative Online Inquiry
KO28571 KANK2 Knockout cell line (HEK293) Human KANK2 1:3~1:6 Negative Online Inquiry
KO28572 KANK2 Knockout cell line (A549) Human KANK2 1:3~1:4 Negative Online Inquiry

Background

KANK2 Gene Knockout Cell Lines are genetically modified cell lines that have had the KANK2 gene, which encodes a protein involved in various cellular processes, effectively rendered non-functional. This innovative product serves as a vital tool for researchers investigating the role of KANK2 in cellular signaling pathways, cytoskeletal organization, and disease mechanisms, particularly in cancer and neurodegenerative disorders.

The primary function of KANK2 involves cytoskeletal regulation and interacting with proteins that are critical for cellular architecture and signaling. By utilizing knockout cell lines, researchers can dissect the physiological roles of KANK2 with greater precision, employing assays that assess cell proliferation, migration, and apoptosis. The absence of KANK2 allows for comprehensive analysis of downstream effects on signal transduction pathways, thereby elucidating its contribution to pathological conditions.

The scientific significance of KANK2 Gene Knockout Cell Lines cannot be overstated, as they facilitate a deeper understanding of gene function and protein interactions, providing insights that are essential for the development of targeted therapies. These lines are particularly valuable in oncology research, where elucidating the complex roles of gene dysregulation can lead to novel treatment strategies. Furthermore, they serve as robust models for studying neurodevelopmental processes and the impact on neurological health.

Compared to traditional genetic manipulation methods, such as RNA interference or transient transfection, KANK2 Gene Knockout Cell Lines offer permanent and stable gene disruption, ensuring consistent and reproducible results. This reliability translates into more accurate experimental outcomes, reducing variability and increasing the credibility of research findings.

For researchers and clinicians, the utility of KANK2 Gene Knockout Cell Lines lies not only in advancing knowledge of KANK2's biological functions but also in their potential to innovate therapeutic approaches. Our company stands at the forefront of cellular biology, delivering high-quality genetic models that empower scientific exploration and innovation. By choosing our KANK2 Gene Knockout Cell Lines, you are investing in a proven resource designed to accelerate your research endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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