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JMJD7-PLA2G4B Knockout Cell Lines

Gene: JMJD7-PLA2G4B

Official Full Name: JMJD7-PLA2G4B readthroughprovided by HGNC

Gene Summary: This locus represents naturally-occurring readthrough transcription between the neighboring jumonji domain containing 7 (JMJD7) and phospholipase A2, group IVB (cytosolic) (PLA2G4B) genes. Readthrough transcripts encode fusion proteins that share amino acid sequence with each individual gene product, including a partial JmjC domain and downstream C2 and phospholipase A2 domains. Alternatively spliced transcript variants have been observed. [provided by RefSeq, Oct 2013]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO08884 JMJD7-PLA2G4B Knockout cell line (HeLa) Human JMJD7-PLA2G4B 1:3~1:6 Negative Online Inquiry
KO08885 JMJD7-PLA2G4B Knockout cell line (HCT 116) Human JMJD7-PLA2G4B 1:2~1:4 Negative Online Inquiry

Background

JMJD7-PLA2G4B Gene Knockout Cell Lines represent a significant advance in genetic research, providing platforms for the functional analysis of the JMJD7 and PLA2G4B genes. These specialized cell lines have been engineered to possess a complete knockout of these genes, enabling researchers to investigate the roles they play in cellular processes, signaling pathways, and disease mechanisms. The primary function of these knockout cell lines is to elucidate gene function by observing phenotypic changes resulting from the absence of the targeted genes. This allows scientists to explore the implications of JMJD7 and PLA2G4B in various biological contexts, including cancer, neurodegeneration, and inflammation.

The scientific significance of JMJD7-PLA2G4B Gene Knockout Cell Lines is underscored by their application in both basic research and clinical settings. For example, understanding the mechanisms through which JMJD7 interacts with chromatin dynamics and the impact of PLA2G4B on inflammatory responses can provide insights that drive novel therapeutic strategies. These cell lines can thus facilitate drug discovery and development by serving as valuable tools for high-throughput screening and pathway analysis.

What sets these knockout cell lines apart from conventional models is their precision and specificity in gene targeting, resulting in minimal off-target effects and reproducible experimental outcomes. Additionally, their accessibility for various experimental techniques, including CRISPR/Cas9 knock-in methodologies, makes them a versatile choice for researchers looking to expand their genetic studies.

For researchers and clinicians focused on gene function and its relationship to human health, JMJD7-PLA2G4B Gene Knockout Cell Lines represent a critical resource. These cell lines not only enhance understanding of genetic roles but also streamline experimental workflows and improve the robustness of experimental findings.

Our commitment to advancing research through high-quality biological products is evidenced by our expertise in developing and providing innovative models, such as the JMJD7-PLA2G4B Gene Knockout Cell Lines, tailored for the needs of the scientific community.

Please note that all services are for research use only. Not intended for any clinical use.

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