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JAKMIP3 Knockout Cell Lines

Gene: JAKMIP3

Official Full Name: Janus kinase and microtubule interacting protein 3provided by HGNC

Gene Summary: Predicted to enable kinase binding activity and microtubule binding activity. Predicted to be located in Golgi apparatus and membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO16861 JAKMIP3 Knockout cell line (A549) Human JAKMIP3 1:3~1:4 Negative Online Inquiry

Background

JAKMIP3 Gene Knockout Cell Lines are genetically engineered cell lines specifically developed to disable the JAKMIP3 gene, which encodes a protein implicated in various signaling pathways related to immune response and cell differentiation. By utilizing CRISPR-Cas9 technology, these cell lines provide researchers with a robust tool for studying the precise functions of JAKMIP3 in cellular contexts, enabling enhanced understanding of its role in human health and disease.

The key function of JAKMIP3 gene knockout cell lines lies in their ability to mimic loss-of-function mutations, allowing for the dissection of the intracellular signaling cascades that depend on this gene. When JAKMIP3 is knocked out, researchers can observe alterations in cell behavior, such as changes in cytokine signaling, proliferation, and apoptosis, which are crucial for understanding conditions like autoimmune disorders and cancers.

The scientific importance of these cell lines is underscored by their applications in both basic and translational research. They serve as reliable models for elucidating the mechanistic pathways that govern immune responses and could potentially lead to novel therapeutic strategies targeting related diseases. Furthermore, these knockout cell lines are ideal for compound screening and biomarker discovery, enhancing their utility in the drug development process.

Compared to alternative models, JAKMIP3 gene knockout cell lines offer the significant advantage of specificity and reproducibility, minimizing off-target effects and providing researchers with consistent and reliable results. Additionally, they are scalable for high-throughput applications, making them suitable for large-scale experiments.

In conclusion, JAKMIP3 Gene Knockout Cell Lines represent a vital resource for researchers and clinicians looking to deepen their understanding of immune signaling pathways and associated pathologies. Our company specializes in delivering high-quality biological products that empower scientific innovation, and we are committed to supporting the research community with cutting-edge tools like these knockout cell lines.

Please note that all services are for research use only. Not intended for any clinical use.

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