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ITPRIPL2 Knockout Cell Lines

Gene: ITPRIPL2

Official Full Name: ITPRIP like 2provided by HGNC

Gene Summary: Predicted to be located in membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO16866 ITPRIPL2 Knockout cell line (HeLa) Human ITPRIPL2 1:3~1:6 Negative Online Inquiry
KO16867 ITPRIPL2 Knockout cell line (HCT 116) Human ITPRIPL2 1:2~1:4 Negative Online Inquiry
KO16868 ITPRIPL2 Knockout cell line (HEK293) Human ITPRIPL2 1:3~1:6 Negative Online Inquiry
KO16869 ITPRIPL2 Knockout cell line (A549) Human ITPRIPL2 1:3~1:4 Negative Online Inquiry

Background

ITPRIPL2 Gene Knockout Cell Lines are specifically engineered cellular models that enable researchers to investigate the implications of ITPRIPL2 gene deletion in various biological processes. This product involves the targeted disruption of the ITPRIPL2 gene, which encodes for an intracellular protein implicated in calcium signaling and has been linked to several pathophysiological conditions. The cell lines are generated using advanced CRISPR-Cas9 technology, ensuring precise and efficient gene editing, which is essential for studying the resultant phenotypic alterations caused by the knockout.

The primary mechanism of these cell lines lies in their ability to facilitate detailed investigations into calcium homeostasis, cellular signaling pathways, and their roles in diseases such as tumorigenesis and neurodegenerative disorders. By utilizing ITPRIPL2 knockout cells, scientists can elucidate the gene's function and its interactions with other cellular components, thus advancing our understanding of critical pathways involved in health and disease.

In terms of scientific importance, these cell lines can serve as valuable tools for drug discovery and therapeutic research, allowing for the screening of novel compounds targeting calcium signaling pathways. Their applications extend to both fundamental research and translational medicine, bridging the gap between laboratory findings and clinical relevance.

Compared to traditional methods, such as transient transfection approaches or RNA interference, ITPRIPL2 Gene Knockout Cell Lines provide a stable, long-term model that allows for repeated experimentation without the variability associated with transient systems. This stability ensures more reliable data and enhances reproducibility across experiments, which are crucial for high-quality research.

Researchers and clinicians can greatly benefit from incorporating these knockout cell lines into their studies, as they provide a robust platform for generating insights that could lead to novel therapeutic interventions. The meticulous design and validation of these cell lines highlight their relevance in advancing our understanding of calcium-related pathologies.

At our company, we specialize in providing high-quality biological products tailored to the needs of the research community. With a commitment to scientific excellence and innovation, our ITPRIPL2 Gene Knockout Cell Lines exemplify our dedication to empowering researchers and facilitating breakthroughs in biomedical science.

Please note that all services are for research use only. Not intended for any clinical use.

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