Gene: ITFG1
Official Full Name: integrin alpha FG-GAP repeat containing 1provided by HGNC
Gene Summary: Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO25793 | ITFG1 Knockout cell line (HeLa) | Human | ITFG1 | 1:3~1:6 | Negative | Online Inquiry |
KO25794 | ITFG1 Knockout cell line (HCT 116) | Human | ITFG1 | 1:2~1:4 | Negative | Online Inquiry |
KO25795 | ITFG1 Knockout cell line (HEK293) | Human | ITFG1 | 1:3~1:6 | Negative | Online Inquiry |
KO25796 | ITFG1 Knockout cell line (A549) | Human | ITFG1 | 1:3~1:4 | Negative | Online Inquiry |
ITFG1 Gene Knockout Cell Lines are specifically engineered cellular models that have undergone targeted gene disruption of the ITFG1 gene, which encodes the Itch-Family Transcription Factor 1, a protein implicated in various cellular functions, including transcriptional regulation and cellular signaling pathways. This knockout model serves as a pivotal tool for researchers seeking to investigate the role of ITFG1 in cellular processes such as proliferation, differentiation, and apoptosis.
The core functionality of these cell lines is rooted in their ability to facilitate the study of gene function by eliminating the expression of ITFG1, thereby providing insights into the downstream effects of its absence. Researchers can utilize these cell lines to elucidate the mechanisms by which ITFG1 influences key biological processes, particularly in the context of disease states such as cancer and metabolic disorders. The knockout approach allows for the dissection of specific pathways that may be altered due to the lack of ITFG1, promoting a deeper understanding of its regulatory functions.
The scientific importance of ITFG1 Gene Knockout Cell Lines is significant in both research and clinical settings. They serve as essential models for drug discovery, gene therapy approaches, and functional genomics, enabling detailed assessments of how targeting the ITFG1 gene may yield therapeutic benefits. These models provide a robust platform to identify potential biomarkers for disease progression and treatment response, thus bridging basic research with clinical implications.
Compared to alternative models, such as wild-type or overexpression systems, the ITFG1 knockout lines offer a distinct advantage by providing a clear and direct examination of the gene's role in a native cellular environment, without the confounding effects of a functioning ITFG1 gene. This specificity enhances the reliability and reproducibility of experimental outcomes, making these cell lines invaluable in translational research.
For researchers and clinicians, ITFG1 Gene Knockout Cell Lines represent a critical resource for advancing knowledge in gene function and developing innovative therapeutic strategies. Their unique capabilities not only allow for a deeper exploration of fundamental biology but also support the translation of findings into practical applications that can improve patient outcomes.
Our company is dedicated to delivering high-quality biological products that empower researchers and clinicians alike. With a focus on innovation and precision, we provide advanced cell line models that facilitate breakthrough discoveries in the life sciences.
Please note that all services are for research use only. Not intended for any clinical use.
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