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IRAK1BP1 Knockout Cell Lines

Gene: IRAK1BP1

Official Full Name: interleukin 1 receptor associated kinase 1 binding protein 1provided by HGNC

Gene Summary: Predicted to enable signaling adaptor activity. Predicted to be involved in canonical NF-kappaB signal transduction. Predicted to be located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO26421 IRAK1BP1 Knockout cell line (HeLa) Human IRAK1BP1 1:3~1:6 Negative Online Inquiry
KO26422 IRAK1BP1 Knockout cell line (HCT 116) Human IRAK1BP1 1:2~1:4 Negative Online Inquiry
KO26423 IRAK1BP1 Knockout cell line (HEK293) Human IRAK1BP1 1:3~1:6 Negative Online Inquiry
KO26424 IRAK1BP1 Knockout cell line (A549) Human IRAK1BP1 1:3~1:4 Negative Online Inquiry

Background

IRAK1BP1 Gene Knockout Cell Lines are specialized cellular models that have been genetically engineered to disrupt the expression of the IRAK1BP1 gene, a critical component in various signal transduction pathways, particularly those involved in immune responses. These knockout cell lines facilitate in-depth studies of the IRAK1BP1 protein’s functional roles and its impact on cellular processes, including inflammation, apoptosis, and innate immune signaling.

The primary mechanism of these knockout cell lines is the targeted deletion of the IRAK1BP1 gene, achieved through advanced gene editing techniques such as CRISPR-Cas9. This disruption allows researchers to observe the resultant phenotypic changes—providing valuable insights into the gene’s contribution to immune regulation and the broader implications of its loss on cellular behavior and signaling dynamics. Such models are indispensable for elucidating the mechanistic roles of IRAK1BP1 and for developing potential therapeutic strategies that can manipulate immune responses in various diseases.

The scientific importance of IRAK1BP1 Gene Knockout Cell Lines extends to both research and clinical applications. In the realm of immunology, these cell lines enable the exploration of novel pathways and targets for intervention in autoimmune disorders, infectious diseases, and cancer. The findings derived from studies utilizing these cell lines can guide the development of innovative treatments and diagnostic tools, bridging fundamental research with clinical relevance.

One of the distinct advantages of IRAK1BP1 Gene Knockout Cell Lines is their high specificity in targeting the IRAK1BP1 pathway without affecting other signaling cascades, unlike broad-spectrum inhibitors. This precision provides researchers with a more reliable model to delineate the effects of IRAK1BP1 modulation on cell function. Additionally, these knockout cell lines come with comprehensive support, including detailed protocols and characterization data, ensuring that users have all the necessary resources to maximize their studies.

For researchers and clinicians looking to enhance their understanding of immune signaling and to develop targeted therapeutic strategies, IRAK1BP1 Gene Knockout Cell Lines represent an invaluable tool. Their ability to provide critical insights into immune mechanisms underscores their role in advancing biological research.

Our company is a pioneer in the field of genetic engineering, dedicated to delivering high-quality biological products. By leveraging cutting-edge techniques and rigorous quality control, we ensure that our IRAK1BP1 Gene Knockout Cell Lines meet the highest standards for excellence, empowering scientists in their quest for discovery.

Please note that all services are for research use only. Not intended for any clinical use.

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