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IQCA1 Knockout Cell Lines

Gene: IQCA1

Official Full Name: dynein regulatory complex subunit 11provided by HGNC

Gene Summary: The protein encoded by this gene is a member of the ATPases Associated with diverse cellular Activities (AAA) superfamily. Members of this superfamily, found in all organisms, participate in a large number of cellular processes and contain the ATPase module consisting of an alpha-beta-alpha core domain and the Walker A and B motifs of the P-loop NTPases. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO16897 IQCA1 Knockout cell line (HeLa) Human IQCA1 1:3~1:6 Negative Online Inquiry

Background

IQCA1 Gene Knockout Cell Lines are a specialized tool for researchers focused on unraveling the cellular and molecular functions associated with the IQCA1 gene. By using CRISPR-Cas9 technology, these cell lines have been genetically modified to disable the expression of the IQCA1 gene, allowing for the study of its functional roles in cellular processes and pathways.

The key mechanism of action relies on the precise alteration of the genomic DNA, resulting in a complete loss-of-function phenotype. This capability enables researchers to observe the downstream effects of IQCA1 deficiency, facilitating investigations into various biological phenomena such as cell growth, differentiation, and response to external stimuli. The gene knockout cell lines provide an invaluable model for studying diseases where IQCA1 may play a role, including certain cancers or neurological disorders.

The scientific importance of IQCA1 Gene Knockout Cell Lines lies in their applicability across multiple research domains, from molecular biology to pharmacology. They serve as critical platforms for drug discovery, functional genomics, and developmental biology, giving researchers insights that could lead to novel therapeutic strategies.

Compared to traditional gene knockout approaches, the IQCA1 Gene Knockout Cell Lines present several advantages. They offer high specificity and efficiency due to the precise nature of CRISPR technology, minimizing off-target effects that can confound results. Additionally, these cell lines provide consistent genetic background and phenotype, which is crucial for reproducibility in scientific experiments.

For researchers and clinicians, the value of the IQCA1 Gene Knockout Cell Lines lies in their ability to streamline experimental processes and enhance the discovery of biological mechanisms. By utilizing these advanced cell models, users can accelerate their research timelines and improve the reliability of their findings.

As a company dedicated to advancing life sciences research, we offer an extensive portfolio of validated biological products, including the IQCA1 Gene Knockout Cell Lines, each meticulously developed to meet the evolving needs of the scientific community. Our expertise ensures that our customers receive not only high-quality products but also the support necessary to achieve impactful discoveries.

Please note that all services are for research use only. Not intended for any clinical use.

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