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INTS15 Knockout Cell Lines

Gene: INTS15

Official Full Name: integrator complex subunit 15provided by HGNC

Gene Summary: Part of integrator complex. Is active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO16898 INTS15 Knockout cell line (HeLa) Human INTS15 1:3~1:6 Negative Online Inquiry
KO16899 INTS15 Knockout cell line (HCT 116) Human INTS15 1:2~1:4 Negative Online Inquiry
KO16900 INTS15 Knockout cell line (HEK293) Human INTS15 1:3~1:6 Negative Online Inquiry
KO16901 INTS15 Knockout cell line (A549) Human INTS15 1:3~1:4 Negative Online Inquiry

Background

INTS15 Gene Knockout Cell Lines represent a groundbreaking advancement in cellular biology research, specifically designed to facilitate the study of gene function and associated biological pathways. These cell lines have been meticulously developed by employing CRISPR-Cas9 gene editing technology to create targeted disruptions in the INTS15 gene, an essential component involved in RNA splicing and gene expression regulation. This knockout approach allows researchers to effectively isolate the effects of INTS15 and investigate its role in various cellular processes, from transcriptional regulation to cellular response to stress.

The primary mechanism by which INTS15 gene knockout cell lines operate hinges on the creation of specific mutations that disrupt protein synthesis of the INTS15 gene, thereby halting its normal functions. This disruption provides a unique platform for analyzing the consequent phenotypic alterations and helps elucidate the impact on associated pathways, including those involved in cancer progression and neurodegenerative diseases.

The scientific importance of these cell lines is profound; they enable researchers to uncover novel therapeutic targets and biomarkers, thereby enhancing our understanding of complex disease mechanisms. In clinical settings, they can be invaluable for drug discovery and development, allowing for high-throughput screening of compounds that may restore normal function in cells lacking INTS15 activity.

What sets the INTS15 Gene Knockout Cell Lines apart from alternative models is their specificity and reliability. Unlike traditional knockdown approaches that provide transient effects, our knockout lines offer stable genetic changes, ensuring consistency in experimental results. Additionally, these cell lines come characterized and validated for various assays, streamlining workflow for researchers and clinicians alike.

For researchers and clinicians seeking to advance their understanding of gene interaction networks or develop novel therapeutic strategies, the INTS15 Gene Knockout Cell Lines provide an essential tool. With our expertise in developing high-quality biological products, we are dedicated to supporting the growth of innovative research and fostering breakthroughs in genomics and personalized medicine.

Please note that all services are for research use only. Not intended for any clinical use.

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