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INO80E Knockout Cell Lines

Gene: INO80E

Official Full Name: INO80 complex subunit Eprovided by HGNC

Gene Summary: Involved in several processes, including chromatin remodeling; regulation of chromosome organization; and regulation of nucleobase-containing compound metabolic process. Located in nucleolus and nucleoplasm. Part of Ino80 complex. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO16915 INO80E Knockout cell line (HeLa) Human INO80E 1:3~1:6 Negative Online Inquiry
KO16916 INO80E Knockout cell line (HCT 116) Human INO80E 1:2~1:4 Negative Online Inquiry
KO16917 INO80E Knockout cell line (HEK293) Human INO80E 1:3~1:6 Negative Online Inquiry
KO16918 INO80E Knockout cell line (A549) Human INO80E 1:3~1:4 Negative Online Inquiry

Background

INO80E Gene Knockout Cell Lines are specialized biological tools created through CRISPR/Cas9 gene editing technology to inactivate the INO80E gene in various cellular contexts. These cell lines enable researchers to investigate the functional roles of the INO80E gene, which is crucial in chromatin remodeling, DNA repair, and cell cycle regulation. By selectively knocking out this gene, scientists can study its impact on cellular processes and elucidate its contributions to disease mechanisms, particularly in cancer and genetic disorders.

The unique mechanism of these knockout cell lines lies in their precise genetic modification. The CRISPR/Cas9 system allows for a targeted disruption of the INO80E gene, resulting in loss-of-function mutations that can be analyzed in functional assays. This specificity is essential for minimizing off-target effects, providing researchers with high-confidence data regarding INO80E's role in various biological pathways.

The scientific importance of INO80E Gene Knockout Cell Lines extends to applications in both basic and translational research. In academic laboratories, these models serve as fundamental tools for studying gene function and identifying potential therapeutic targets. Additionally, in clinical research, they can pave the way for novel interventions by revealing how modulation of the INO80E pathway might impact disease progression and treatment response.

Compared to alternative gene editing techniques or cell lines, INO80E Gene Knockout Cell Lines offer several distinct advantages. Their customization allows for the generation of specific cellular contexts, such as different genetic backgrounds or environmental conditions, enhancing their versatility in various experimental setups. Moreover, they are developed under rigorous quality control measures, ensuring consistency and reliability across studies.

For researchers and clinicians, the INO80E Gene Knockout Cell Lines provide an invaluable resource that streamlines the exploration of gene function and its implications in health and disease. The ability to manipulate and study specific genetic targets contributes significantly to the advancement of molecular biology and therapeutic development.

Our company specializes in producing high-quality biological research tools, guaranteed through our years of expertise in genetic engineering and cell biology. We are committed to supporting the scientific community with innovative solutions that facilitate groundbreaking discoveries in understanding gene functions and their roles in disease.

Please note that all services are for research use only. Not intended for any clinical use.

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