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INKA1 Knockout Cell Lines

Gene: INKA1

Official Full Name: inka box actin regulator 1provided by HGNC

Gene Summary: Enables protein kinase binding activity and protein serine/threonine kinase inhibitor activity. Predicted to act upstream of or within neural tube development. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO16927 INKA1 Knockout cell line (HCT 116) Human INKA1 1:2~1:4 Negative Online Inquiry
KO16928 INKA1 Knockout cell line (A549) Human INKA1 1:3~1:4 Negative Online Inquiry

Background

INKA1 Gene Knockout Cell Lines are specialized, engineered cell lines that have undergone precise genetic alteration to disrupt the expression of the INKA1 gene, a crucial regulator of cellular processes involved in proliferation, differentiation, and responses to stress. By employing advanced CRISPR-Cas9 technology, these cell lines enable researchers to study the specific biological roles played by INKA1 while providing insights into gene function and the underlying mechanisms of various diseases.

The key function of INKA1 gene knockout is to create a cellular environment devoid of INKA1 expression, allowing for the analysis of genetic interactions and pathway alterations that occur as a result of its absence. The mechanistic understanding gained from studies using these cell lines is invaluable for elucidating the fundamental biological processes in cellular biology as well as understanding pathological conditions where INKA1 may serve as a critical player.

In research and clinical settings, INKA1 Gene Knockout Cell Lines are significant tools for drug discovery, disease modeling, and functional genomics. They can facilitate investigations into cell signaling pathways, cancer biology, and regenerative medicine, ultimately aiding in the development of novel therapeutic strategies. Their application extends to high-throughput screening assays, allowing for the rapid identification of compounds that can modulate the actions of target pathways influenced by INKA1.

Compared to traditional methods of gene knockout, our INKA1 cell lines offer enhanced precision, consistency, and reproducibility. The use of CRISPR-Cas9 technology minimizes off-target effects and maximizes efficiencies in gene disruption, ensuring reliable experimental outcomes. Additionally, these cell lines are designed for easy integration into diverse experimental workflows, making them suitable for a range of applications in molecular biology and therapeutic development.

Researchers and clinicians will find INKA1 Gene Knockout Cell Lines to be a valuable asset for advancing their work, providing a unique opportunity to dissect gene function and its implications in health and disease. By incorporating these cell lines into their research, users can unlock new avenues for scientific discovery and innovation.

Our company prides itself on its expertise in developing high-quality biological products tailored to meet the evolving needs of the life sciences community, ensuring that our products, including the INKA1 Gene Knockout Cell Lines, are at the forefront of scientific advancement.

Please note that all services are for research use only. Not intended for any clinical use.

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