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IFIT2 Knockout Cell Lines

Gene: IFIT2

Official Full Name: interferon induced protein with tetratricopeptide repeats 2provided by HGNC

Gene Summary: Enables RNA binding activity. Involved in antiviral innate immune response and positive regulation of apoptotic process. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO37111 IFIT2 Knockout cell line (HeLa) Human IFIT2 1:3~1:6 Negative Online Inquiry
KO37112 IFIT2 Knockout cell line (A549) Human IFIT2 1:3~1:4 Negative Online Inquiry

Background

IFIT2 Gene Knockout Cell Lines are genetically modified cellular systems that facilitate the study of the interferon-induced protein with tetratricopeptide repeats 2 (IFIT2). These cell lines have been engineered to suppress the expression of the IFIT2 gene, providing researchers with a powerful tool to investigate the role of IFIT2 in various biological processes, especially in the context of viral infections and immune response.

The core function of IFIT2 is to play a crucial role in innate immunity, particularly by controlling the cellular response to viral infections. By knocking out this gene, researchers can dissect the pathways involved in the immune response, enabling them to study downstream effects on gene expression, apoptosis, and viral replication. The knockout mechanism employed in these cell lines involves targeted gene editing technologies, such as CRISPR/Cas9, ensuring precise and efficient disruption of the IFIT2 gene.

The scientific significance of IFIT2 Gene Knockout Cell Lines is profound, as they allow for enhanced understanding of gene function in both basic and applied research settings. These cell lines are invaluable for studying viral pathogens and developing therapeutic strategies, thus having implications in vaccine development and antiviral therapies. Moreover, they can be employed in drug discovery, revealing potential targets for therapeutic intervention.

A key advantage of using our IFIT2 Gene Knockout Cell Lines over existing alternatives lies in their validated knockout efficiency and functional characterization, which are critical for ensuring reliable experimental outcomes. Unlike conventional cell lines, which may have residual IFIT2 activity, our product guarantees a complete disruption, leading to more conclusive experimental data.

For researchers and clinicians focused on exploring innate immune mechanisms or developing novel antiviral strategies, IFIT2 Gene Knockout Cell Lines represent an indispensable product that enhances experimental rigor and biological relevance. Backed by extensive expertise in genetic engineering and cellular biology, our company is committed to delivering high-quality biological products that empower scientific discovery and innovation.

Please note that all services are for research use only. Not intended for any clinical use.

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