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IER5 Knockout Cell Lines

Gene: IER5

Official Full Name: immediate early response 5provided by HGNC

Gene Summary: This gene encodes a protein that is similar to other immediate early response proteins. In the mouse, a similar gene may play an important role in mediating the cellular response to mitogenic signals. Studies in rats found the expression of a similar gene to be increased after waking and sleep deprivation. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO22751 IER5 Knockout cell line (HeLa) Human IER5 1:3~1:6 Negative Online Inquiry
KO22752 IER5 Knockout cell line (HCT 116) Human IER5 1:2~1:4 Negative Online Inquiry
KO22753 IER5 Knockout cell line (HEK293) Human IER5 1:3~1:6 Negative Online Inquiry
KO22754 IER5 Knockout cell line (A549) Human IER5 1:3~1:4 Negative Online Inquiry

Background

IER5 Gene Knockout Cell Lines are engineered cellular models specifically designed for the study of the IER5 gene, an important regulator associated with cell growth and stress responses. These cell lines are generated through CRISPR/Cas9 gene-editing technology, which allows for precise deletions of the IER5 gene, creating a reliable platform to investigate the gene's functions and its role in various biological processes.

The primary function of the IER5 gene is implicated in cellular stress response mechanisms, impacting cell proliferation and survival under adverse conditions. By utilizing these knockout cell lines, researchers can dissect pathways involving the IER5 gene, assess the compensatory mechanisms cells harness in the absence of this gene, and explore how its disruption affects cellular behavior such as apoptosis, DNA repair, and oncogenesis.

The scientific importance of IER5 Gene Knockout Cell Lines extends beyond basic research; they hold potential applications in drug discovery, cancer research, and regenerative medicine. Understanding the role of IER5 opens doors to novel therapeutic strategies targeting diseases where this gene's expression is dysregulated.

One significant advantage of using these specialized cell lines compared to traditional models is their specificity and reproducibility. By eliminating the variable expression of the IER5 gene, researchers can achieve more consistent results and a deeper understanding of the gene's interactions. Furthermore, these cell lines are developed under stringent quality control measures, ensuring high viability and performance standards.

For researchers and clinicians pursuing breakthroughs in genetic and cellular biology, the value of IER5 Gene Knockout Cell Lines lies in their ability to provide insights that can drive innovation in treatment strategies. With a firm commitment to advancing the field of biomedical research, our company harnesses cutting-edge gene-editing technologies and validation processes to deliver superior biological products that empower the research community.

Please note that all services are for research use only. Not intended for any clinical use.

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