Gene: ID1
Official Full Name: inhibitor of DNA binding 1provided by HGNC
Gene Summary: The protein encoded by this gene is a helix-loop-helix (HLH) protein that can form heterodimers with members of the basic HLH family of transcription factors. The encoded protein has no DNA binding activity and therefore can inhibit the DNA binding and transcriptional activation ability of basic HLH proteins with which it interacts. This protein may play a role in cell growth, senescence, and differentiation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO11547 | ID1 Knockout cell line (HeLa) | Human | ID1 | 1:3~1:6 | Negative | Online Inquiry |
KO11548 | ID1 Knockout cell line (HCT 116) | Human | ID1 | 1:2~1:4 | Negative | Online Inquiry |
KO11549 | ID1 Knockout cell line (HEK293) | Human | ID1 | 1:3~1:6 | Negative | Online Inquiry |
KO11550 | ID1 Knockout cell line (A549) | Human | ID1 | 1:3~1:4 | Negative | Online Inquiry |
ID1 Gene Knockout Cell Lines are specialized cellular models engineered to lack the expression of the Inhibitor of DNA Binding 1 (ID1) gene, an essential regulator involved in various biological processes, including cell differentiation, proliferation, and the pathogenesis of several diseases. The targeted knockout of this gene is achieved through advanced CRISPR-Cas9 technology, which ensures precise gene editing with minimal off-target effects.
These cell lines function as invaluable tools for elucidating the role of ID1 in cellular signaling pathways, particularly those related to cancer biology, cardiovascular development, and stem cell differentiation. By disrupting the ID1 gene, researchers can study the consequent phenotypic changes, providing insights into how ID1 contributes to tumorigenesis and other pathological conditions. Additionally, these models facilitate the exploration of potential therapeutic strategies that aim to modulate ID1 activity.
The scientific importance of ID1 Gene Knockout Cell Lines extends to their applications in both basic and translational research settings. They offer researchers the ability to investigate ID1's involvement in stress responses and developmental processes, ultimately aiding in the identification of novel biomarkers and therapeutic targets. Furthermore, these models present a robust platform for drug screening and validation, particularly in studies seeking to understand the mechanisms of resistance in cancer therapies.
One of the standout advantages of our ID1 Gene Knockout Cell Lines is their development through rigorously validated methods, ensuring high efficiency and reproducibility. Unlike other alternatives that may rely on transient knockdown strategies, which provide inconsistent results, our knockout lines offer stable gene disruption. This distinction ensures that researchers can derive reliable data over extended experimental timelines.
For researchers, clinicians, and biotechnology companies, the value of ID1 Gene Knockout Cell Lines lies in their ability to deliver robust insights into complex biological processes and disease mechanisms. Moreover, they allow for the exploration of innovative therapeutic avenues, thereby enhancing experimental rigor and contributing to the advancement of healthcare solutions.
Our company is committed to providing high-quality, research-ready biological products that empower scientists to achieve groundbreaking discoveries. With a focus on precision and reliability, we stand as a trusted partner in research and clinical development, ensuring that our products meet the highest standards of scientific excellence.
Please note that all services are for research use only. Not intended for any clinical use.
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