Home / HSPA4L Knockout Cell Lines

HSPA4L Knockout Cell Lines

Gene: HSPA4L

Official Full Name: heat shock protein family A (Hsp70) member 4 likeprovided by HGNC

Gene Summary: The protein encoded by this gene is heat shock inducible and may act as a chaperone. The encoded protein can protect the heat-shocked cell against the harmful effects of aggregated proteins. This gene is highly expressed in leukemia cells and may be a good target for therapeutic intervention. Several transcripts encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO20210 HSPA4L Knockout cell line (HeLa) Human HSPA4L 1:3~1:6 Negative Online Inquiry
KO20211 HSPA4L Knockout cell line (HCT 116) Human HSPA4L 1:2~1:4 Negative Online Inquiry
KO20212 HSPA4L Knockout cell line (HEK293) Human HSPA4L 1:3~1:6 Negative Online Inquiry
KO20213 HSPA4L Knockout cell line (A549) Human HSPA4L 1:3~1:4 Negative Online Inquiry

Background

HSPA4L Gene Knockout Cell Lines are specialized cellular models engineered to lack the expression of the HSPA4L gene, a member of the heat shock protein family known for its role in protein folding and protection against cellular stress. By utilizing CRISPR/Cas9 gene-editing technology, these knockout cell lines provide researchers with a precise tool to study the functional implications of HSPA4L absence on cellular mechanisms, stress responses, and disease pathophysiology.

The key functions of the HSPA4L gene knockout cell lines revolve around their capacity to reveal the physiological and pathological processes influenced by HSPA4L. These cell lines can serve as experimental platforms to investigate cellular responses under stress conditions, explore the implications of disrupted protein homeostasis, and identify potential protective roles of HSPA4L in cancer and neurodegenerative diseases. Researchers can leverage these insights to uncover novel therapeutic targets and enhance understanding of disease mechanisms.

In research and clinical applications, HSPA4L gene knockout cell lines are invaluable for elucidating the gene's involvement in critical biological processes. Their use in drug discovery and development, particularly in the context of stress-related conditions, allows for the identification of compounds that may restore normal cellular function. Furthermore, these cell lines can facilitate biomarker discovery and provide a basis for identifying novel therapeutic strategies.

Compared to traditional cell models, HSPA4L gene knockout cell lines offer a high degree of specificity and reliability, ensuring reproducibility in experiments. These models enable more targeted investigations and eliminate confounding factors associated with partial gene expression, thereby enhancing the robustness of findings.

For researchers and clinicians, the value of HSPA4L gene knockout cell lines is profound; they represent a cutting-edge approach to explore the intricacies of gene function and their implications in human health. This aligns with ongoing efforts to devise strategies for precision medicine and personalized therapeutic interventions.

Our company is committed to advancing biological research and therapeutic innovation, providing high-quality gene knockout cell lines that empower scientists with the tools necessary to push the boundaries of discovery in molecular and cellular biology.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.