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HROB Knockout Cell Lines

Gene: HROB

Official Full Name: homologous recombination factor with OB-foldprovided by HGNC

Gene Summary: Predicted to enable single-stranded DNA binding activity. Involved in DNA synthesis involved in DNA repair and interstrand cross-link repair. Located in site of DNA damage. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO20592 HROB Knockout cell line (HeLa) Human HROB 1:3~1:6 Negative Online Inquiry
KO20593 HROB Knockout cell line (HCT 116) Human HROB 1:2~1:4 Negative Online Inquiry
KO20594 HROB Knockout cell line (HEK293) Human HROB 1:3~1:6 Negative Online Inquiry
KO20595 HROB Knockout cell line (A549) Human HROB 1:3~1:4 Negative Online Inquiry

Background

HROB Gene Knockout Cell Lines are genetically engineered cellular models that have been specifically designed to facilitate targeted gene disruption studies. In these cell lines, the HROB gene has been selectively inactivated through the application of the CRISPR-Cas9 genome editing technology, providing researchers with a powerful tool to investigate the functional roles of the HROB gene in various biological processes and disease states.

The primary mechanism of action involves the precise introduction of double-strand breaks in the target gene, which are then repaired in a way that results in the deletion or insertion of nucleotides. This disruption allows for the observation of cellular changes and phenotypic variations attributable to the absence or impairment of HROB gene expression, thus providing significant insights into gene function, pathways, and regulatory networks.

The scientific importance of HROB Gene Knockout Cell Lines is underscored by their role in advancing our understanding of cellular mechanisms in basic research as well as in clinical applications, particularly in cancer biology and developmental studies. By utilizing these knockout models, researchers can elucidate the HROB gene’s involvement in oncogenesis, gene regulation, and cellular differentiation, paving the way for potential therapeutic interventions.

What sets HROB Gene Knockout Cell Lines apart from traditional genetic models is their ease of use, rapid generation, and high reproducibility. Unlike conventional knockout methodologies that may be labor-intensive and time-consuming, these ready-to-use cell lines streamline experimental workflows and significantly reduce the time required to establish functional studies.

For researchers and clinicians, the availability of HROB Gene Knockout Cell Lines enhances the ability to conduct high-throughput screenings and validate therapeutic targets with greater efficiency and accuracy. Their unique combination of specificity and versatility makes them an invaluable asset in both academic research laboratories and pharmaceutical development environments.

Backed by our extensive expertise in genetic engineering and a commitment to supporting scientific advancement, our company ensures that researchers have access to high-quality biological products like the HROB Gene Knockout Cell Lines, facilitating breakthroughs in genomics and biomedicine.

Please note that all services are for research use only. Not intended for any clinical use.

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