Gene: HOXD9
Official Full Name: homeobox D9provided by HGNC
Gene Summary: This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that removed the entire HOXD gene cluster or 5' end of this cluster have been associated with severe limb and genital abnormalities. The exact role of this gene has not been determined. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO02790 | HOXD9 Knockout cell line (HeLa) | Human | HOXD9 | 1:3~1:6 | Negative | Online Inquiry |
KO02791 | HOXD9 Knockout cell line (HEK293) | Human | HOXD9 | 1:3~1:6 | Negative | Online Inquiry |
HOXD9 Gene Knockout Cell Lines are genetically engineered cell lines in which the HOXD9 gene has been systematically disrupted through precise gene-editing techniques such as CRISPR-Cas9. This product serves as a powerful tool for researchers studying the functional roles of the HOXD9 gene, which is known to play a critical role in developmental processes, cell differentiation, and various oncogenic pathways. By achieving a knockout of this gene, researchers can observe and quantify the resultant phenotypic changes, providing insights into the gene's involvement in both normal physiology and disease states.
The key mechanism of action behind the HOXD9 Gene Knockout Cell Lines lies in the targeted deletion of the HOXD9 coding sequences. This disruption allows for the systematic investigation of gene function by elucidating the downstream effects of HOXD9 absence on cellular processes, including apoptosis, proliferation, and migration. Such cell lines are particularly valuable in cancer research, developmental biology, and regenerative medicine, where understanding the role of HOXD9 can lead to breakthroughs in therapeutic interventions.
In the realm of scientific research and clinical applications, these knockout cell lines offer several significant advantages, including high specificity and reproducibility in experimental settings. Unlike traditional gene silencing methods such as RNA interference, the complete knockout achieves a permanent genetic alteration, providing a more definitive understanding of gene function over time. Additionally, HOXD9 Gene Knockout Cell Lines can be employed in high-throughput screening, drug discovery, and pathway analysis, thereby accelerating research timelines and improving the robustness of data.
For researchers and clinicians, the value of HOXD9 Gene Knockout Cell Lines extends beyond basic research; they are pivotal in unlocking new avenues for targeted therapies and personalized medicine approaches. Understanding how HOXD9 operates at a molecular level could lead to novel interventions in diseases where its pathway is dysregulated.
Our company is dedicated to advancing scientific research through high-quality biological products, and we pride ourselves on our expertise in gene editing technologies. HOXD9 Gene Knockout Cell Lines exemplify our commitment to providing researchers with innovative tools to enhance their studies and foster groundbreaking discoveries in the biomedical field.
Please note that all services are for research use only. Not intended for any clinical use.
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