Gene: HOXC11
Official Full Name: homeobox C11provided by HGNC
Gene Summary: This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The product of this gene binds to a promoter element of the lactase-phlorizin hydrolase. It also may play a role in early intestinal development. An alternatively spliced variant encoding a shorter isoform has been described but its full-length nature has not been determined. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO37240 | HOXC11 Knockout cell line (HeLa) | Human | HOXC11 | 1:3~1:6 | Negative | Online Inquiry |
HOXC11 Gene Knockout Cell Lines are specialized cellular models engineered to specifically lack the HOXC11 gene, a member of the homeobox gene family known to play a critical role in embryonic development and cellular differentiation. By utilizing CRISPR-Cas9 gene editing technology, these knockout cell lines enable researchers to investigate the precise functions and regulatory mechanisms of HOXC11 in various biological processes.
The key functions of HOXC11 include its involvement in the orchestration of developmental pathways and its potential role in oncogenesis, which makes knockout models invaluable for studying gene function in both normal and pathological states. The targeted disruption of this gene allows for controlled experimental conditions where researchers can observe the effects of HOXC11 absence on cell behavior, differentiation potential, and response to external stimuli, providing insights into developmental biology and cancer research.
In terms of scientific significance, HOXC11 Gene Knockout Cell Lines are crucial in both academic and clinical research settings. They serve as robust tools for understanding genetic influences in diseases, testing therapeutic strategies, and elucidating drug responses linked to HOXC11. The ability to create isogenic cell lines offers advantages in the realm of personalized medicine and functional genomics.
What sets our HOXC11 Gene Knockout Cell Lines apart from alternatives is their high specificity and efficiency of gene editing, ensuring a complete knockout of the gene with minimal off-target effects. Additionally, our extensive validation protocols ensure the reliability and reproducibility of experimental results, fostering confidence in scientific findings.
For researchers and clinicians seeking to enhance their studies of gene function and disease models, the HOXC11 Gene Knockout Cell Lines present a unique opportunity to advance understanding and drive innovation. Our company prides itself on its commitment to providing high-quality biological products backed by unparalleled technical support and expertise in genetic engineering.
Please note that all services are for research use only. Not intended for any clinical use.
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