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HOMER1 Knockout Cell Lines

Gene: HOMER1

Official Full Name: homer scaffold protein 1provided by HGNC

Gene Summary: This gene encodes a member of the homer family of dendritic proteins. Members of this family regulate group 1 metabotrophic glutamate receptor function. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO08210 HOMER1 Knockout cell line (HeLa) Human HOMER1 1:3~1:6 Negative Online Inquiry
KO08211 HOMER1 Knockout cell line (HCT 116) Human HOMER1 1:2~1:4 Negative Online Inquiry
KO08212 HOMER1 Knockout cell line (HEK293) Human HOMER1 1:3~1:6 Negative Online Inquiry
KO08213 HOMER1 Knockout cell line (A549) Human HOMER1 1:3~1:4 Negative Online Inquiry

Background

HOMER1 Gene Knockout Cell Lines are genetically modified cellular models specifically engineered to lack the HOMER1 gene, which encodes for a member of the Homer family of proteins involved in synaptic signaling and neuronal development. These knockout cell lines serve as a powerful tool in molecular biology and neuroscience research, allowing scientists to investigate the role of HOMER1 in cellular processes such as synaptic plasticity, neurotransmission, and brain function.

The primary function of HOMER1 involves the facilitation of interactions between group 1 metabotropic glutamate receptors and intracellular signaling pathways. By employing the CRISPR-Cas9 gene-editing technology, our HOMER1 Gene Knockout Cell Lines demonstrate an effective deletion of this gene, enabling researchers to examine the absence of HOMER1's regulatory effects on synaptic events and overall cellular behavior. These models provide insights into the altered signaling pathways and functional outcomes that arise from HOMER1 deletion, enhancing our understanding of synaptic dynamics and their implications in neurodevelopmental and psychiatric disorders.

In a clinical or research setting, the importance of using HOMER1 Gene Knockout Cell Lines cannot be overstated. They represent a critical asset for studies involving synaptic dysfunctions associated with conditions such as autism, schizophrenia, and Alzheimer’s disease. By elucidating the pathways influenced by HOMER1, researchers can potentially unveil novel therapeutic targets, paving the way for innovative treatments.

Compared to other gene knockout models, our HOMER1 Cell Lines offer unmatched specificity and consistency, reducing background noise and improving the reliability of experimental outcomes. The extensive validation processes employed ensure a high level of confidence in reproducibility. Furthermore, our product is backed by a team of leading researchers and geneticists, ensuring that our clients receive not only superior products but also continuous support and expert guidance for their experimental designs.

When advancing your research endeavors or clinical inquiries, consider the HOMER1 Gene Knockout Cell Lines as a strategic tool to provide deeper insights into synaptic biology. Our commitment to scientific excellence and innovation positions us as leaders in the production of high-quality biological products tailored for the demands of modern research.

Please note that all services are for research use only. Not intended for any clinical use.

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