Gene: HMX3
Official Full Name: H6 family homeobox 3provided by HGNC
Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including embryo implantation; maternal process involved in female pregnancy; and neuromuscular process controlling balance. Predicted to be located in chromatin. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO20238 | HMX3 Knockout cell line (HeLa) | Human | HMX3 | 1:3~1:6 | Negative | Online Inquiry |
HMX3 Gene Knockout Cell Lines are specialized cellular models that have been genetically modified to disrupt the expression of the HMX3 gene, which encodes a protein implicated in various developmental processes, particularly in the context of neural and craniofacial development. These knockout cell lines serve as indispensable tools for researchers looking to elucidate the gene's function in biological pathways and disease mechanisms.
The primary function of HMX3 Gene Knockout Cell Lines is to enable the study of the gene's role in cellular processes such as differentiation, proliferation, and response to external stimuli. By employing CRISPR-Cas9 technology, these cell lines exhibit a permanent modification that allows for rigorous analysis of the downstream effects resulting from HMX3 loss-of-function. This mechanistic insight is critical for identifying potential therapeutic targets in congenital abnormalities and cancers linked to HMX3 dysregulation.
The scientific importance of these cell lines lies in their applications across various research and clinical settings, particularly in developmental biology, genetics, and regenerative medicine. By facilitating the investigation of the HMX3 gene's involvement in crucial pathways, these knockout models can significantly contribute to understanding pathophysiological conditions and advancing therapeutic approaches.
Compared to alternative gene disruption methods, HMX3 Gene Knockout Cell Lines offer precise and predictable outcomes, ensuring reproducibility and reliability. Their established background provides a robust platform for functional assays, high-throughput screening, and drug discovery, delivering a more nuanced understanding of gene functions.
For researchers and clinicians, the value of HMX3 Gene Knockout Cell Lines extends beyond mere experimentation; they represent a key resource for impactful discoveries that could lead to breakthroughs in genetic therapies and personalized medicine. By leveraging these innovative models, users can enhance their research prowess and expand their functional genomics capabilities.
Our company prides itself on its extensive expertise in providing high-quality, cutting-edge biological products tailored for the scientific community. We are committed to supporting your research endeavors with reliable and precise tools, such as our HMX3 Gene Knockout Cell Lines, that empower innovative solutions in biomedical research.
Please note that all services are for research use only. Not intended for any clinical use.
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