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HMSD Knockout Cell Lines

Gene: HMSD

Official Full Name: histocompatibility minor serpin domain containingprovided by HGNC

Gene Summary: This gene encodes a serpin-domain containing protein that may function as a serine protease inhibitor. This gene is primarily expressed in cells of myeloid lineage. A polymorphism in this gene may result in the expression a splice variant that encodes a minor histocompatibility antigen. [provided by RefSeq, Oct 2010]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO17074 HMSD Knockout cell line (HCT 116) Human HMSD 1:2~1:4 Negative Online Inquiry

Background

HMSD Gene Knockout Cell Lines are engineered cellular platforms designed to silence specific genes, allowing researchers to investigate gene function and elucidate cellular pathways. Each cell line is meticulously developed using CRISPR-Cas9 technology, ensuring precise modifications that lead to the complete knockout of target genes. This genetic alteration enables a deeper understanding of gene roles in various biological processes, including signal transduction, metabolic pathways, and disease mechanisms.

The key mechanism of action involves the introduction of guide RNA (gRNA) that targets the gene of interest alongside the Cas9 nuclease, which induces double-strand breaks in the DNA. The subsequent cellular repair processes often result in insertions or deletions that disrupt gene function. This targeted approach ensures high specificity and efficiency, enabling researchers to observe the phenotypic consequences of gene loss, thereby facilitating hypothesis-driven research.

The scientific importance of HMSD Gene Knockout Cell Lines is profound, as they serve as valuable tools in basic and applied research. In clinical settings, these cell lines can be leveraged to model diseases, test pharmaceutical interventions, and contribute to gene therapy advancements. Their application spans cancer research, neurobiology, immunology, and beyond, making them indispensable in contemporary biomedical investigations.

What sets HMSD Gene Knockout Cell Lines apart from alternatives is their rigorous validation, comprehensive documentation, and availability across a diverse range of gene targets. Unlike other products, our cell lines are accompanied by detailed user protocols and experimental guidelines, ensuring ease of use and reproducibility. Researchers and clinicians can trust the precision and reliability of our products to yield consistent and reliable data.

In reconsidering the value of HMSD Gene Knockout Cell Lines, it becomes evident that they are essential for cutting-edge research and development. Their ability to provide insights into gene function and therapeutic targets makes them a cornerstone for both academic and pharmaceutical laboratories. Our company excels in delivering high-quality biological products, continually striving to innovate and meet the evolving needs of the scientific community.

Please note that all services are for research use only. Not intended for any clinical use.

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