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HLX Knockout Cell Lines

Gene: HLX

Official Full Name: H2.0 like homeoboxprovided by HGNC

Gene Summary: Enables sequence-specific DNA binding activity. Predicted to be involved in signal transduction. Predicted to act upstream of or within several processes, including embryonic digestive tract morphogenesis; enteric nervous system development; and regulation of T-helper cell differentiation. Predicted to be located in chromatin. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO37346 HLX Knockout cell line (HeLa) Human HLX 1:3~1:6 Negative Online Inquiry
KO37347 HLX Knockout cell line (HCT 116) Human HLX 1:2~1:4 Negative Online Inquiry
KO37348 HLX Knockout cell line (HEK293) Human HLX 1:3~1:6 Negative Online Inquiry
KO37349 HLX Knockout cell line (A549) Human HLX 1:3~1:4 Negative Online Inquiry

Background

HLX Gene Knockout Cell Lines are genetically engineered cells specifically designed to facilitate the study of gene function through the targeted disruption of HLX gene expression. Utilizing advanced CRISPR-Cas9 gene editing technology, these cell lines exhibit a complete knockout of the HLX gene, enabling researchers to explore its role in various biological processes, disease models, and therapeutic targets. The mechanism of action involves the introduction of a guide RNA (gRNA) that directs the Cas9 endonuclease to the target HLX gene, resulting in double-strand breaks that are subsequently repaired incorrectly, thus leading to mutations that disrupt gene function.

The scientific importance of HLX Gene Knockout Cell Lines lies in their applications in cancer research, developmental biology, and regenerative medicine. By providing insights into HLX's role in cellular differentiation, proliferation, and tumorigenesis, these tools serve as vital resources for elucidating complex biological pathways and identifying novel therapeutic interventions. In clinical settings, understanding HLX function can have implications in targeted treatments for disorders associated with aberrant gene expression or regulation.

Compared to alternative knockout systems, such as transgenic animals or transient RNA interference, HLX Gene Knockout Cell Lines offer several advantages. They provide a versatile, cost-effective, and rapid model for gene function studies while minimizing ethical concerns associated with animal models. These cell lines are also amenable to high-throughput screening, allowing researchers to easily assess the impacts of drug candidates and genetic modifications.

For researchers and clinicians focused on gene function and its implications in health and disease, HLX Gene Knockout Cell Lines present invaluable tools for advancing scientific discovery and therapeutic development. With a commitment to high-quality biological products, our company leverages extensive expertise in genetic engineering to deliver cutting-edge solutions that empower your research endeavors and unlock new possibilities in life sciences.

Please note that all services are for research use only. Not intended for any clinical use.

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