Gene: HEXIM1
Official Full Name: HEXIM P-TEFb complex subunit 1provided by HGNC
Gene Summary: Expression of this gene is induced by hexamethylene-bis-acetamide in vascular smooth muscle cells. This gene has no introns. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO31666 | HEXIM1 Knockout cell line (HeLa) | Human | HEXIM1 | 1:3~1:6 | Negative | Online Inquiry |
KO31667 | HEXIM1 Knockout cell line (HCT 116) | Human | HEXIM1 | 1:2~1:4 | Negative | Online Inquiry |
KO31668 | HEXIM1 Knockout cell line (HEK293) | Human | HEXIM1 | 1:3~1:6 | Negative | Online Inquiry |
KO31669 | HEXIM1 Knockout cell line (A549) | Human | HEXIM1 | 1:3~1:4 | Negative | Online Inquiry |
HEXIM1 Gene Knockout Cell Lines are genetically modified cell lines in which the HEXIM1 gene has been knocked out, providing researchers with a powerful tool to study the role of this gene in various biological processes. HEXIM1, known to be involved in the regulation of transcription and RNA polymerase II activity, plays crucial roles in cellular proliferation, differentiation, and responses to stress. By introducing specific knockout strategies, these cell lines allow for in-depth exploration of the downstream effects of HEXIM1 deficiency, facilitating a greater understanding of its contributions to cellular function.
The primary mechanism of action involves the disruption of HEXIM1's interaction with key cellular pathways, such as the positive transcription elongation factor b (P-TEFb) complex. This interruption can significantly influence transcriptional dynamics, making these cell lines invaluable for experiments aimed at elucidating transcriptional regulation under both normal and pathological conditions. Researchers can investigate the implications of HEXIM1 loss in disease models, shedding light on potential therapeutic targets and biomarkers.
In clinical and research settings, HEXIM1 gene knockout cell lines offer numerous applications. They are pivotal in studying cancer biology, where aberrations in transcriptional control are common, and are also beneficial in modeling viral infections, given HEXIM1's role in chromatin remodeling and antiviral responses.
What sets HEXIM1 gene knockout cell lines apart from conventional models is their precision and specificity, allowing for accurate mimicking of HEXIM1 loss. This specificity leads to data that are more reliable and reproducible, providing researchers with a comparative advantage in elucidating the precise role of HEXIM1.
For researchers and clinicians aiming to expand their understanding of gene regulation and its implications in health and disease, HEXIM1 Gene Knockout Cell Lines are an indispensable resource. They not only enhance experimental rigor but also open avenues for innovative research in molecular biology and therapeutic development. Our company specializes in providing high-quality, validated biological products, ensuring that scientists have access to superior tools for their groundbreaking work.
Please note that all services are for research use only. Not intended for any clinical use.
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