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HEXD Knockout Cell Lines

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO17123 HEXD Knockout cell line (HeLa) Human HEXD 1:3~1:6 Negative Online Inquiry
KO17124 HEXD Knockout cell line (HCT 116) Human HEXD 1:2~1:4 Negative Online Inquiry
KO17125 HEXD Knockout cell line (HEK293) Human HEXD 1:3~1:6 Negative Online Inquiry
KO17126 HEXD Knockout cell line (A549) Human HEXD 1:3~1:4 Negative Online Inquiry

Background

HEXD Gene Knockout Cell Lines are precisely engineered cellular models designed to facilitate the investigation of the HEXD gene's biological functions and its pathological implications. These cell lines have undergone targeted gene editing through advanced CRISPR/Cas9 technology, enabling the effective knockout of the HEXD gene, which plays a crucial role in the metabolism of certain glycosphingolipids. By disrupting this gene, researchers can mimic disease states associated with HEXD deficiency, such as GM2 gangliosidosis, thereby providing insights into the molecular mechanisms underpinning lysosomal storage disorders.

The core functionality of HEXD Gene Knockout Cell Lines lies in their ability to produce observable phenotypic changes resulting from the absence of HEXD. This enables elucidation of the gene's role in cellular pathways such as lipid metabolism, signaling, and autophagy. By studying these alterations, scientists can identify potential therapeutic targets and biomarkers that may be vital for developing treatment modalities for related diseases.

In terms of scientific importance, HEXD Gene Knockout Cell Lines serve as invaluable tools in both basic and translational research settings. They can be employed in drug screening assays, pathophysiological studies, and gene therapy research, making them essential for advancing the understanding of complex genetic disorders related to HEXD function.

What sets our HEXD Gene Knockout Cell Lines apart from alternatives is their high degree of specificity and validation. Each cell line is rigorously characterized to confirm the knockout's efficiency and the resulting phenotypic outcomes, allowing researchers to trust the reproducibility of their findings. Furthermore, our comprehensive support and technical guidance ensure users can maximize the utility of our product, simplifying experimental design and interpretation.

For researchers, clinicians, and pharmaceutical developers, the HEXD Gene Knockout Cell Lines offer a powerful resource for advancing understanding and treatment of glycosphingolipid-related diseases. Partnering with us not only grants access to cutting-edge biotechnological products but also reflects our commitment to supporting innovative research through years of expertise in genetic engineering and cellular biology. We are dedicated to fostering scientific discovery with reliable, high-quality biological tools that drive results.

Please note that all services are for research use only. Not intended for any clinical use.

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