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HEATR5B Knockout Cell Lines

Gene: HEATR5B

Official Full Name: HEAT repeat containing 5Bprovided by HGNC

Gene Summary: Predicted to be involved in endocytosis; protein localization; and retrograde transport, endosome to Golgi. Located in cytosol and nuclear speck. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO21691 HEATR5B Knockout cell line (HeLa) Human HEATR5B 1:3~1:6 Negative Online Inquiry
KO21692 HEATR5B Knockout cell line (HCT 116) Human HEATR5B 1:2~1:4 Negative Online Inquiry
KO21693 HEATR5B Knockout cell line (HEK293) Human HEATR5B 1:3~1:6 Negative Online Inquiry
KO21694 HEATR5B Knockout cell line (A549) Human HEATR5B 1:3~1:4 Negative Online Inquiry

Background

HEATR5B Gene Knockout Cell Lines are genetically engineered cell lines designed to specifically disrupt the HEATR5B gene, which plays a crucial role in various cellular processes, including RNA metabolism, protein synthesis, and cellular stress responses. Utilizing CRISPR-Cas9 gene editing technology, these cell lines provide a powerful tool for studying the functions associated with the HEATR5B gene and its implications in diseases such as cancer, neurodegenerative disorders, and immunological conditions.

The key mechanism by which HEATR5B knockout cell lines exhibit their functionality lies in the targeted introduction of double-strand breaks at the HEATR5B locus, followed by cellular repair processes that often result in gene disruption. This systematic approach allows researchers to analyze gene function and study the downstream effects of the absence of HEATR5B protein, contributing to a better understanding of various pathways involved in cellular health and disease.

These knockout cell lines hold significant scientific importance in research settings, particularly in functional genomics and drug discovery. They enable the identification of potential pharmacological targets and the validation of therapeutic strategies aimed at modulating the pathways influenced by HEATR5B. In clinical settings, understanding the function of genes like HEATR5B can lead to the development of personalized medicine approaches and improved treatment paradigms for conditions where this gene is implicated.

What distinguishes the HEATR5B Gene Knockout Cell Lines from alternative products is their high specificity, validated performance in a variety of experimental conditions, and their compatibility with several common laboratory techniques. This ensures reliable results, making them a trusted resource for both academic and industry researchers. Moreover, these cell lines come with robust documentation and technical support, enhancing user experience and streamlining research workflows.

For researchers and clinicians seeking to deepen their understanding of gene function and its role in disease, HEATR5B Gene Knockout Cell Lines represent a valuable asset. Our company, specializing in advanced genetic engineering solutions, ensures that these products maintain the highest quality standards and are backed by extensive expertise in molecular biology, empowering users to drive cutting-edge research and innovation in their respective fields.

Please note that all services are for research use only. Not intended for any clinical use.

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