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HAUS2 Knockout Cell Lines

Gene: HAUS2

Official Full Name: HAUS augmin like complex subunit 2provided by HGNC

Gene Summary: The protein encoded by this gene is a subunit of the augmin complex. The augmin complex plays a role in microtubule attachment to the kinetochore and central spindle formation. [provided by RefSeq, Apr 2016]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO17166 HAUS2 Knockout cell line (HeLa) Human HAUS2 1:3~1:6 Negative Online Inquiry
KO17167 HAUS2 Knockout cell line (HCT 116) Human HAUS2 1:2~1:4 Negative Online Inquiry
KO17168 HAUS2 Knockout cell line (HEK293) Human HAUS2 1:3~1:6 Negative Online Inquiry
KO17169 HAUS2 Knockout cell line (A549) Human HAUS2 1:3~1:4 Negative Online Inquiry

Background

HAUS2 Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to study the biological role of the HAUS2 gene, which is crucial for microtubule organization and cellular division. By utilizing CRISPR/Cas9 technology, these cell lines have undergone precise genome editing to create complete knockout models that effectively eliminate HAUS2 function, providing invaluable insight into its involvement in cellular processes such as spindle formation and cytoskeletal dynamics.

The key function of HAUS2 Gene Knockout Cell Lines lies in their ability to serve as a powerful tool for dissecting the molecular pathways influenced by HAUS2. Researchers can utilize these models to understand how the disruption of HAUS2 affects cell proliferation, migration, and overall cellular homeostasis. These cell lines are particularly significant for studies in cancer biology, where aberrations in microtubule dynamics contribute to tumorigenesis and metastasis.

In comparison to traditional siRNA knockdown approaches, HAUS2 Gene Knockout Cell Lines offer several advantages. These include a stable and permanent alteration of the gene of interest, allowing for long-term studies and reducing the possibility of off-target effects seen with transient knockdown strategies. Moreover, they facilitate the creation of a consistent experimental setup which is crucial for reproducible research outcomes.

For researchers and clinicians, the value of HAUS2 Gene Knockout Cell Lines extends to their potential applications in drug discovery, developmental biology, and understanding disease mechanisms at a molecular level. By employing these cell lines, scientists can more effectively pinpoint pharmacological targets and explore therapeutic interventions for diseases tied to microtubule dysfunction.

At [Company Name], we pride ourselves on our extensive expertise in gene editing technologies and our commitment to providing high-quality biological products that enhance research capabilities. Our HAUS2 Gene Knockout Cell Lines exemplify our dedication to supporting advancements in molecular biology and translational research.

Please note that all services are for research use only. Not intended for any clinical use.

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