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HACL1 Knockout Cell Lines

Gene: HACL1

Official Full Name: 2-hydroxyacyl-CoA lyase 1provided by HGNC

Gene Summary: Enables several functions, including 2-hydroxyacyl-CoA lyase activity; ATP binding activity; and cation binding activity. Involved in fatty acid alpha-oxidation; phytanic acid metabolic process; and protein targeting to peroxisome. Located in nucleoplasm and peroxisome. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO28407 HACL1 Knockout cell line (HeLa) Human HACL1 1:3~1:6 Negative Online Inquiry
KO28408 HACL1 Knockout cell line (HCT 116) Human HACL1 1:2~1:4 Negative Online Inquiry
KO28409 HACL1 Knockout cell line (HEK293) Human HACL1 1:3~1:6 Negative Online Inquiry
KO28410 HACL1 Knockout cell line (A549) Human HACL1 1:3~1:4 Negative Online Inquiry

Background

HACL1 Gene Knockout Cell Lines are specialized biological tools that enable researchers to study the functions and pathways regulated by the HACL1 gene, which is implicated in various cellular processes, including metabolic regulation and cell signaling. These genetically modified cell lines have undergone precise gene editing to inactivate the HACL1 gene, facilitating the exploration of its role in human biology and disease models.

The primary function of HACL1 Gene Knockout Cell Lines is to provide a controlled environment for the investigation of the phenotypic outcomes resulting from HACL1 gene disruption. By using CRISPR-Cas9 gene editing technology, these cell lines exhibit a complete knockout of the HACL1 gene, allowing researchers to observe changes in metabolic pathways, cellular proliferation, and response to stressors, thereby elucidating the gene's contribution to both normal physiology and pathological states.

Scientifically, studying HACL1 gene knockout models is critical as they offer valuable insights into metabolic disorders and can help identify potential therapeutic targets in conditions such as cancer, diabetes, and neurodegenerative diseases. The insights gained from these studies are influential in advancing knowledge in both basic and translational research, empowering scientists to develop novel treatment strategies.

One of the unique advantages of HACL1 Gene Knockout Cell Lines lies in their ability to provide reproducible and reliable results that facilitate high-throughput screening of drug candidates and the testing of genetic manipulations. Unlike traditional models, these cell lines eliminate variable expressions from endogenous HACL1, offering a clear and distinct biological readout.

For researchers and clinicians, the value of HACL1 Gene Knockout Cell Lines extends beyond their experimental utility; their use can accelerate the path from hypothesis to discovery, fostering rapid advancements in the understanding of gene function and new treatment methodologies. Additionally, the robust support and expertise offered by our company in developing and optimizing these cell lines ensure that users can gain maximum benefits while minimizing the technical challenges often associated with genetic research.

Trust our extensive expertise in providing high-quality biological products tailored to meet the rigorous demands of contemporary research and clinical applications.

Please note that all services are for research use only. Not intended for any clinical use.

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