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HACD3 Knockout Cell Lines

Gene: HACD3

Official Full Name: 3-hydroxyacyl-CoA dehydratase 3provided by HGNC

Gene Summary: Enables enzyme binding activity and very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase activity. Involved in fatty acid biosynthetic process; positive regulation by virus of viral protein levels in host cell; and positive regulation of viral genome replication. Located in endoplasmic reticulum and nuclear membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO22485 HACD3 Knockout cell line (HeLa) Human HACD3 1:3~1:6 Negative Online Inquiry
KO22486 HACD3 Knockout cell line (HCT 116) Human HACD3 1:2~1:4 Negative Online Inquiry
KO22487 HACD3 Knockout cell line (HEK293) Human HACD3 1:3~1:6 Negative Online Inquiry
KO22488 HACD3 Knockout cell line (A549) Human HACD3 1:3~1:4 Negative Online Inquiry

Background

HACD3 Gene Knockout Cell Lines are genetically engineered cell lines that have been specifically designed to silence the gene encoding for 3-hydroxyacyl-CoA dehydratase 3 (HACD3). This product serves as a powerful model for studying the functional roles of HACD3 in lipid metabolism and cellular processes. By utilizing CRISPR-Cas9 technology, these cell lines ensure precise and efficient gene knockout, enabling researchers to observe the resultant phenotypic and molecular changes.

The primary functions of HACD3 involve the regulation of fatty acid biosynthesis and the modulation of membrane integrity. By knocking out HACD3, researchers can investigate the pathways impacted by its absence, providing insights into lipid metabolism disorders and their potential implications in diseases such as obesity, diabetes, and certain cancers. The use of these cell lines allows for a more in-depth understanding of the physiological roles of HACD3, as well as the consequences of its dysregulation in a controlled environment.

In both research and clinical settings, HACD3 Gene Knockout Cell Lines offer significant advantages over traditional models. They allow for the examination of gene function with high specificity, reducing off-target effects that can confound results. Additionally, the robust nature of these cell lines facilitates consistent experimentation, making them an invaluable resource for studies aimed at identifying therapeutic targets or understanding disease mechanisms.

For researchers and clinicians looking to delve into the complexities of lipid metabolism or explore potential therapeutic strategies, HACD3 Gene Knockout Cell Lines provide a unique and valuable tool. The ability to study altered gene function in a systematic manner accelerates the discovery of novel insights into metabolic diseases and aids in drug development. As a company specializing in high-quality biological products, we are committed to providing researchers with cutting-edge tools that enhance scientific understanding and innovation.

Please note that all services are for research use only. Not intended for any clinical use.

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