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H2BK1 Knockout Cell Lines

Gene: H2BK1

Official Full Name: H2B.K variant histone 1provided by HGNC

Gene Summary: Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Predicted to be located in chromosome and nucleus. Predicted to be part of nucleosome. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO17193 H2BK1 Knockout cell line (HEK293) Human H2BK1 1:3~1:6 Negative Online Inquiry

Background

H2BK1 Gene Knockout Cell Lines are specifically engineered cellular models that enable researchers to study the functions and physiological roles of the H2BK1 gene by eliminating its expression. These cell lines are created through sophisticated gene editing techniques, such as CRISPR-Cas9, resulting in a precise knockout of the H2BK1 gene. This methodology allows for the investigation of H2BK1's contribution to various cellular processes, including chromatin dynamics, gene regulation, and cellular response to environmental stresses.

One of the key functions of H2BK1 is its involvement in the formation of nucleosomes, which are essential for DNA packaging and regulation of gene expression. By utilizing these knockout cell lines, researchers can delve into the implications of H2BK1 loss in cellular mechanisms, shedding light on its potential role in cancer biology, neurodegenerative diseases, and other pathophysiological conditions. The ability to perform comparative studies between wild-type and knockout cell lines facilitates an in-depth understanding of gene function and regulatory networks.

The scientific importance of H2BK1 Gene Knockout Cell Lines is underscored by their broad applicability in both research and clinical settings. For instance, they are invaluable tools for drug discovery, biomarker identification, and validation of therapeutic targets. Investigations that employ H2BK1 knockout models can lead to significant advancements in personalized medicine, particularly in understanding individual variability in response to treatments.

Compared to other gene knockout strategies, H2BK1 Gene Knockout Cell Lines offer notable advantages, including enhanced specificity, reproducibility, and the ability to study long-term effects of gene loss in a controlled environment. Moreover, these cell lines are readily available and easy to handle, making them a practical choice for a variety of experimental designs.

Researchers and clinicians seeking to expand their investigations into gene functions will find immense value in H2BK1 Gene Knockout Cell Lines, as they provide a powerful platform for elucidating complex biological processes and developing novel therapeutic strategies. With our extensive expertise in cell line development and cutting-edge genetic engineering technologies, our company is committed to delivering high-quality biological research products that drive scientific discovery and innovation.

Please note that all services are for research use only. Not intended for any clinical use.

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