Gene: H2AC25
Official Full Name: H2A clustered histone 25provided by HGNC
Gene Summary: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene contain a palindromic termination element. [provided by RefSeq, Aug 2015]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO17206 | H2AC25 Knockout cell line (HeLa) | Human | H2AC25 | 1:3~1:6 | Negative | Online Inquiry |
KO17207 | H2AC25 Knockout cell line (HCT 116) | Human | H2AC25 | 1:2~1:4 | Negative | Online Inquiry |
KO17208 | H2AC25 Knockout cell line (HEK293) | Human | H2AC25 | 1:3~1:6 | Negative | Online Inquiry |
KO17209 | H2AC25 Knockout cell line (A549) | Human | H2AC25 | 1:3~1:4 | Negative | Online Inquiry |
H2AC25 Gene Knockout Cell Lines are a specialized biological product designed for advanced genetic research. These cell lines are generated through precise genome editing techniques, specifically CRISPR-Cas9 technology, to produce stable knockout mutations of the H2AC25 gene. By eliminating the expression of this gene, researchers can study its specific role in cellular processes, gene regulation, and disease mechanisms.
The key function of H2AC25 Gene Knockout Cell Lines lies in their ability to facilitate detailed investigations into the biological effects of H2AC25 disruption. This gene is associated with pivotal cellular functions, including chromatin dynamics and gene expression regulation. Utilizing these cell lines allows researchers to uncover the gene's potential contributions to various physiological and pathological states, such as cancer and developmental disorders.
The scientific importance of these cell lines is substantial in both research and clinical settings. They serve as crucial tools for elucidating the genetic underpinnings of diseases and offer insights that can lead to the development of targeted therapies. Furthermore, the findings garnered from experiments using H2AC25 Knockout Cell Lines can enhance our understanding of genome functioning and contribute to the broader field of genomics.
Compared to alternative products, our H2AC25 Gene Knockout Cell Lines provide a reliable and reproducible model that ensures high specificity and efficiency in gene editing. Our extensive validation processes confirm the knockout's effectiveness, minimizing off-target effects common in other genome editing approaches.
The value of H2AC25 Gene Knockout Cell Lines for researchers and clinicians extends to their versatility in experimental design, making them indispensable for drug discovery and therapeutic development. By leveraging our expertise in gene editing technologies, we deliver a product that not only meets rigorous scientific standards but also fosters innovation in genetic research. Our commitment to quality and precision places us at the forefront of biological product offerings, empowering the scientific community to make groundbreaking discoveries.
Please note that all services are for research use only. Not intended for any clinical use.
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