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GUCA1ANB Knockout Cell Lines

Gene: GUCA1ANB

Official Full Name: ciliary microtubule inner protein 3provided by HGNC

Gene Summary: Predicted to enable calcium ion binding activity. Predicted to be involved in visual perception. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO17226 GUCA1ANB Knockout cell line (HeLa) Human GUCA1ANB 1:3~1:6 Negative Online Inquiry
KO17227 GUCA1ANB Knockout cell line (HCT 116) Human GUCA1ANB 1:2~1:4 Negative Online Inquiry
KO17228 GUCA1ANB Knockout cell line (A549) Human GUCA1ANB 1:3~1:4 Negative Online Inquiry

Background

GUCA1ANB Gene Knockout Cell Lines represent a pivotal advancement in the field of genetic research and biomedicine. These cell lines are specifically engineered to have a targeted knockout of the GUCA1ANB gene, which encodes for guanylate cyclase activating protein, an important regulator in retinal signaling pathways. By eliminating the function of this gene, researchers can elucidate its role in cellular homeostasis and disease mechanisms, particularly in the context of retinal degenerative diseases and other related disorders.

The key function of these knockout cell lines lies in their ability to enable detailed studies of gene function and interaction within biological pathways. The deletion of the GUCA1ANB gene provides a model that mimics certain pathological conditions, allowing scientists to better understand the implications of gene expression changes, signaling alterations, and how these contribute to disease pathogenesis. This mechanistic insight is invaluable for the development of novel therapeutic strategies and for testing potential pharmacological interventions.

In research settings, GUCA1ANB knockout cell lines are indispensable for high-throughput screening and functional assays. Their specific application in the study of retinal physiology can lead to breakthroughs in understanding retinal diseases, which are often multifactorial and poorly understood. Furthermore, the generation of these cell lines adheres to stringent quality control measures, ensuring reproducibility and reliability, which are crucial for obtaining scientifically valid results.

Compared to other alternatives, these knockout lines provide a more precise approach to deconstructing gene function without the confounding effects often observed in more generalized gene knockdown models. This specificity not only enhances the accuracy of data collected but also streamlines the research process, saving valuable time for investigators in a competitive field.

The value of GUCA1ANB Gene Knockout Cell Lines cannot be overstated; they represent an essential tool for researchers and clinicians dedicated to uncovering the intricacies of gene function and disease etiology. As a part of our commitment to advancing scientific innovation, our company leverages extensive expertise in cell line development, ensuring that our products meet the highest standards of scientific rigor and utility.

Please note that all services are for research use only. Not intended for any clinical use.

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