Gene: GTPBP8
Official Full Name: GTP binding protein 8provided by HGNC
Gene Summary: Predicted to enable GTP binding activity; GTPase activity; and metal ion binding activity. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO27181 | GTPBP8 Knockout cell line (HeLa) | Human | GTPBP8 | 1:3~1:6 | Negative | Online Inquiry |
KO27182 | GTPBP8 Knockout cell line (HCT 116) | Human | GTPBP8 | 1:2~1:4 | Negative | Online Inquiry |
KO27183 | GTPBP8 Knockout cell line (HEK293) | Human | GTPBP8 | 1:3~1:6 | Negative | Online Inquiry |
KO27184 | GTPBP8 Knockout cell line (A549) | Human | GTPBP8 | 1:3~1:4 | Negative | Online Inquiry |
GTPBP8 Gene Knockout Cell Lines are advanced biological tools designed to facilitate the study of gene function and its physiological impacts. These cell lines have been genetically engineered to disrupt the GTPBP8 gene, a critical component in various cellular processes, including ribosome assembly, translation regulation, and cellular stress response. By knocking out this gene, researchers can elucidate its role in these processes, particularly in understanding diseases associated with ribosomal dysfunction.
The primary mechanism through which GTPBP8 gene knockout exerts its effects is the inactivation of protein synthesis pathways that depend on GTPBP8's activity. This results in altered cellular phenotypes, enabling researchers to explore pathways related to cell growth, survival, and differentiation. The knockout model also allows for the assessment of potential compensatory mechanisms by other genes, providing a comprehensive picture of cellular resilience or susceptibility.
Scientifically, these cell lines are invaluable tools in both research and clinical settings, offering insights into diseases, including cancer and respiratory disorders, which are related to ribosomal abnormalities. The GTPBP8 knockout model can help in drug discovery, the validation of therapeutic targets, and the development of innovative treatment strategies, enhancing our understanding of disease mechanics.
One distinct advantage of GTPBP8 Gene Knockout Cell Lines is their specificity and reliability compared to other gene editing methods such as CRISPR-Cas9, which may produce off-target effects. Our robust quality assurance protocols ensure high reproducibility and minimal variability between batches, making these cell lines a dependable choice for researchers seeking consistent results.
Researchers and clinicians will find GTPBP8 Gene Knockout Cell Lines incredibly valuable, as they not only streamline experimental workflows but also facilitate groundbreaking discoveries that can lead to novel therapeutic developments. Our company prides itself in providing high-quality biological products backed by years of expertise in genetic engineering and cell biology, ensuring that customers receive reliable and innovative solutions for their research needs.
Please note that all services are for research use only. Not intended for any clinical use.
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