Gene: GTDC1
Official Full Name: glycosyltransferase like domain containing 1provided by HGNC
Gene Summary: Enables tRNA-queuosine(34) beta-mannosyltransferase activity. Involved in regulation of translation and tRNA modification. Located in nucleus. Is active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO20441 | GTDC1 Knockout cell line (HeLa) | Human | GTDC1 | 1:3~1:6 | Negative | Online Inquiry |
KO20442 | GTDC1 Knockout cell line (HCT 116) | Human | GTDC1 | 1:2~1:4 | Negative | Online Inquiry |
KO20443 | GTDC1 Knockout cell line (HEK293) | Human | GTDC1 | 1:3~1:6 | Negative | Online Inquiry |
KO20444 | GTDC1 Knockout cell line (A549) | Human | GTDC1 | 1:3~1:4 | Negative | Online Inquiry |
GTDC1 Gene Knockout Cell Lines are specifically designed cellular models in which the GTDC1 gene has been completely inactivated through precise gene-editing techniques, such as CRISPR-Cas9. This knockout strategy allows researchers to study the gene's function and its implications in various biological processes, providing critical insights into the roles of GTDC1 in cellular metabolism, signal transduction, and disease progression.
The primary function of the GTDC1 knockout cell lines is to serve as a tool for elucidating the biological pathway and molecular mechanisms influenced by the GTDC1 gene. By observing the phenotypic and biochemical changes that occur in these cell lines compared to wild-type counterparts, researchers can gain a deeper understanding of the gene's involvement in cellular processes, such as immune function and response to stress. This information is valuable for identifying potential therapeutic targets for diseases where GTDC1 is implicated.
The scientific significance of GTDC1 knockout cell lines lies in their applicability across a wide range of research disciplines. These cell lines can be utilized in fundamental research, drug discovery, and translational studies, offering insights into the potential impact of GTDC1 on conditions such as autoimmune diseases, cancers, and metabolic disorders. Their relevance in clinical settings extends to personalized medicine, where understanding genetic contributions to diseases can lead to more targeted and effective treatment strategies.
Compared to alternative models, GTDC1 knockout cell lines offer enhanced specificity as they mimic a true null state of the gene, making them more reliable for functional studies. Additionally, these cell lines provide consistency and reproducibility in experimental setups, thereby significantly reducing the variability often seen in other models.
For researchers and clinicians, the value of GTDC1 Gene Knockout Cell Lines lies in their capacity to advance knowledge and foster innovation in genetic research and therapeutic development. As leaders in the field of biotechnology, our company is committed to providing high-quality and reliable biological products, ensuring that our customers have access to the tools necessary for groundbreaking research and clinical advancements.
Please note that all services are for research use only. Not intended for any clinical use.
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