Gene: GSPT2
Official Full Name: G1 to S phase transition 2provided by HGNC
Gene Summary: This gene encodes a GTPase that belongs to the GTP-binding elongation factor family. The encoded protein is a polypeptide release factor that complexes with eukaryotic peptide chain release factor 1 to mediate translation termination. This protein may also be involved in mRNA stability.[provided by RefSeq, Mar 2010]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO28991 | GSPT2 Knockout cell line (HEK293) | Human | GSPT2 | 1:3~1:6 | Negative | Online Inquiry |
KO28992 | GSPT2 Knockout cell line (A549) | Human | GSPT2 | 1:3~1:4 | Negative | Online Inquiry |
GSPT2 Gene Knockout Cell Lines are specialized cellular models engineered to specifically disable the expression of the GSPT2 gene, which encodes for a critical protein associated with translational regulation and stress response in eukaryotic cells. By utilizing a state-of-the-art CRISPR-Cas9 gene editing technology, these cell lines serve as powerful tools for elucidating the biological roles of GSPT2 in various cellular processes, including mRNA degradation, protein synthesis, and the cellular response to stressors.
The key function of GSPT2 involves its participation in the termination of translation and the regulation of mRNA stability. In the context of research and clinical applications, the GSPT2 knockout cell lines enable scientists to investigate the pathways and mechanisms by which GSPT2 contributes to cell viability and proliferation under both standard and adverse conditions. Such investigations can reveal insights into diseases characterized by dysregulated protein synthesis, such as cancer, providing invaluable information that might inform therapeutic strategies.
The scientific importance of GSPT2 knockout cell lines cannot be overstated. They offer researchers the opportunity to assess the functional consequences of GSPT2 loss in a controlled environment, making them ideal for studies on cell signaling, stress responses, and developmental biology. In clinical settings, these cell lines can facilitate drug discovery and development by serving as models for screening compounds that target translational pathways.
Compared to other gene knockout systems, our GSPT2 Gene Knockout Cell Lines are validated for consistency and reliability, offering superior performance metrics. The robust nature of our engineered cell lines allows researchers to achieve reproducible results, thereby accelerating the pace of discovery and innovation.
The value of GSPT2 Gene Knockout Cell Lines lies in their ability to bridge gaps in research pertaining to essential cellular functions and pathogenic mechanisms. Researchers and clinicians alike will benefit from the depth of understanding these cell lines provide, empowering them to develop targeted interventions.
Our company is committed to advancing scientific knowledge and innovation through high-quality biological products. With a focus on precision and excellence, we ensure our offerings meet the diverse needs of the research community and contribute to groundbreaking discoveries in molecular and cellular biology.
Please note that all services are for research use only. Not intended for any clinical use.
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