Gene: GRAMD4
Official Full Name: GRAM domain containing 4provided by HGNC
Gene Summary: GRAMD4 is a mitochondrial effector of E2F1 (MIM 189971)-induced apoptosis (Stanelle et al., 2005 [PubMed 15565177]).[supplied by OMIM, Jan 2011]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO04441 | GRAMD4 Knockout cell line (HeLa) | Human | GRAMD4 | 1:3~1:6 | Negative | Online Inquiry |
KO04442 | GRAMD4 Knockout cell line (HCT 116) | Human | GRAMD4 | 1:2~1:4 | Negative | Online Inquiry |
KO04443 | GRAMD4 Knockout cell line (HEK293) | Human | GRAMD4 | 1:3~1:6 | Negative | Online Inquiry |
KO04444 | GRAMD4 Knockout cell line (A549) | Human | GRAMD4 | 1:3~1:4 | Negative | Online Inquiry |
GRAMD4 Gene Knockout Cell Lines are specialized cellular systems that have been engineered to lack the GRAMD4 gene, which is implicated in various signaling pathways and cellular processes, including immune response and membrane dynamics. These knockout cell lines serve as invaluable tools for understanding the specific contributions of GRAMD4 in cellular behavior and disease mechanisms, facilitating precise investigations into its role in physiological and pathological contexts.
The key function of GRAMD4 Gene Knockout Cell Lines lies in their ability to provide a controlled environment for studying the fallout of GRAMD4 deficiency. Researchers can assess alterations in cellular signaling, membrane stability, and other metabolic functions without the confounding effects of the GRAMD4 protein. This allows for clearer delineation of GRAMD4's role in critical processes such as cellular proliferation, apoptosis, and phagocytosis. The absence of GRAMD4 can also reveal compensatory mechanisms that may be activated in other pathways, offering deeper insights into cellular resilience and vulnerability.
In the scientific landscape, these knockout cell lines are crucial for research applications spanning basic biology to translational medicine. By enabling the study of GRAMD4’s involvement in diseases such as cancer, autoimmune disorders, and infections, these tools accelerate the discovery of novel therapeutic targets and treatment strategies. They provide researchers with the capability to validate hypotheses regarding gene function in a highly reproducible manner, fostering innovative approaches in biomarker discovery and drug development.
The unique selling points of GRAMD4 Gene Knockout Cell Lines include their specificity, reliability, and the ability to integrate seamlessly into existing experimental frameworks. Unlike traditional gene editing approaches, which can be time-consuming and less precise, these ready-to-use knockout cell lines facilitate immediate experimental progression, saving valuable time and resources while ensuring consistency in results.
For researchers and clinicians aiming to deepen their understanding of cell function and disease mechanisms, GRAMD4 Gene Knockout Cell Lines represent a crucial asset. The clarity and specificity they afford can lead to groundbreaking discoveries that may translate into effective therapeutic advancements.
Our company prides itself on providing high-quality biological products backed by extensive expertise in genetic engineering and cell line development. With a commitment to supporting innovative research, we ensure that our offerings empower scientists with the tools necessary to drive advancements in the life sciences.
Please note that all services are for research use only. Not intended for any clinical use.
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