Home / GPR75 Knockout Cell Lines

GPR75 Knockout Cell Lines

Gene: GPR75

Official Full Name: G protein-coupled receptor 75provided by HGNC

Gene Summary: GPR75 is a member of the G protein-coupled receptor family. GPRs are cell surface receptors that activate guanine-nucleotide binding proteins upon the binding of a ligand.[supplied by OMIM, Jul 2002]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO00212 GPR75 Knockout cell line (HEK293) Human GPR75 1:3~1:6 Negative Online Inquiry
KO31398 GPR75 Knockout cell line (HeLa) Human GPR75 1:3~1:6 Negative Online Inquiry
KO31399 GPR75 Knockout cell line (HCT 116) Human GPR75 1:2~1:4 Negative Online Inquiry
KO31400 GPR75 Knockout cell line (A549) Human GPR75 1:3~1:4 Negative Online Inquiry

Background

GPR75 Gene Knockout Cell Lines are specifically engineered cellular models that have had the GPR75 gene inactivated, allowing researchers to study the gene's functions and its role in various biological processes. These knockout cell lines serve as a powerful tool in elucidating the molecular mechanisms at play in both normal physiology and disease states, especially in neurological and metabolic contexts where GPR75 may be implicated.

By utilizing techniques such as CRISPR/Cas9 or other gene-editing technologies, GPR75 Gene Knockout Cell Lines develop an understanding of the gene's contribution to cellular signaling pathways and regulatory networks. The loss of GPR75 can help clarify its involvement in processes such as appetite regulation, energy homeostasis, and potential links to obesity and other metabolic disorders. Such insights are crucial for scientists seeking to develop novel therapeutic strategies or investigate the pathophysiology of related diseases.

The scientific importance of these knockout cell lines extends into both academic research and clinical applications. They enable drug discovery processes by serving as reliable assay systems for testing pharmacological agents targeting GPR75-related pathways. Compared to alternative cell lines that maintain GPR75 expression, knockout lines provide a clearer, more distinct phenotype, facilitating more straightforward interpretation of data and enhancing reproducibility in results.

The unique selling points of GPR75 Gene Knockout Cell Lines include their customization and specificity, allowing researchers to explore a broad range of phenotypic outcomes associated with GPR75's absence. This product addresses the critical need for precision models in understanding complex biological interactions, thereby appealing to researchers and clinicians focused on genetics and metabolic disease.

With extensive experience and expertise in the development of advanced cellular models, our company is committed to providing high-quality biological products that empower researchers in their quest for scientific discovery.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.