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GPR50 Knockout Cell Lines

Gene: GPR50

Official Full Name: G protein-coupled receptor 50provided by HGNC

Gene Summary: This gene product belongs to the G-protein coupled receptor 1 family. Even though this protein shares similarity with the melatonin receptors, it does not bind melatonin, however, it inhibits melatonin receptor 1A function through heterodimerization. Polymorphic variants of this gene have been associated with bipolar affective disorder in women. [provided by RefSeq, Jan 2010]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
GP00598 GPR50 gRNA3-gRNA4 KO plasmid GPR50 $850
KO00826 GPR50 knockout cell line (293T) Human GPR50 1:3~1:6 Negative Online Inquiry
KO17306 GPR50 Knockout cell line (HEK293) Human GPR50 1:3~1:6 Negative Online Inquiry

Background

GPR50 Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to study the function of the GPR50 gene, a member of the G protein-coupled receptor family. This product offers researchers a powerful tool for investigating the biological role of GPR50 in various physiological processes, including circadian rhythm regulation, metabolism, and neuronal function.

The key mechanism by which these knockout cell lines operate is through the deletion of the GPR50 gene, which allows for the comprehensive assessment of GPR50's influence on cellular signaling pathways. By examining these knockout models, researchers can identify the downstream effects of GPR50 absence on cell behavior, receptor interaction, and signaling cascades, ultimately leading to insights that are vital for understanding the gene's role in health and disease.

The scientific importance of GPR50 Gene Knockout Cell Lines extends to various applications within both research and clinical settings. Researchers are utilizing these models to explore the gene's involvement in conditions such as obesity, diabetes, and mood disorders, thus contributing to the development of targeted therapies and personalized medicine approaches. The insights gained from these cell lines have the potential to lead to novel interventions that can improve patient outcomes.

Compared to other genetic manipulation methods, GPR50 Gene Knockout Cell Lines stand out due to their precision and reliability. Unlike transient transfection techniques that may yield inconsistent results, these stable knockout lines ensure reproducibility, enhancing the robustness of experimental findings. Additionally, they provide a straightforward platform for high-throughput screening, enabling the rapid assessment of compounds that may modulate GPR50-related pathways.

For researchers and clinicians, the GPR50 Gene Knockout Cell Lines represent a unique and invaluable resource that can lead to significant advancements in understanding complex biological systems. The ability to reliably investigate the role of this specific gene opens avenues for innovative research and therapeutic strategies.

Our company specializes in the development and supply of high-quality biological research tools, ensuring that scientists have access to cutting-edge resources. With a commitment to excellence and innovation, we are dedicated to supporting research that drives progress in the life sciences.

Please note that all services are for research use only. Not intended for any clinical use.

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