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GPR160 Knockout Cell Lines

Gene: GPR160

Official Full Name: G protein-coupled receptor 160provided by HGNC

Gene Summary: Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Located in plasma membrane. Part of receptor complex. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO27925 GPR160 Knockout cell line (HCT 116) Human GPR160 1:2~1:4 Negative Online Inquiry
KO27926 GPR160 Knockout cell line (HEK293) Human GPR160 1:3~1:6 Negative Online Inquiry
KO27927 GPR160 Knockout cell line (A549) Human GPR160 1:3~1:4 Negative Online Inquiry

Background

GPR160 Gene Knockout Cell Lines are genetically engineered cell lines that have had the GPR160 gene inactivated, allowing researchers to study the function and pathways associated with this G-protein-coupled receptor (GPCR) in detail. GPR160 is implicated in various physiological processes and has been linked to metabolic functions and several disease states. By utilizing GPR160 knockout cell lines, researchers can investigate the receptor's role in cellular signaling, its interactions with ligands, and its impact on downstream signaling pathways.

These cell lines enable scientists to dissect the mechanisms by which GPR160 influences cell behavior, particularly in the context of energy homeostasis and hormonal regulation. The knockout models serve as an excellent tool for elucidating how the absence of GPR160 affects cellular responses to stimuli, which can lead to the identification of potential therapeutic targets.

The scientific importance of GPR160 knockout cell lines extends to both fundamental research and clinical applications. They are particularly valuable in pharmacology and drug development, where understanding the nuances of receptor interactions can inform the creation of new therapeutic strategies for metabolic disorders, obesity, and related comorbidities.

What sets GPR160 knockout cell lines apart from other models, such as wild-type or knockdown systems, is their complete functional removal of the GPR160 gene, offering a more accurate representation of the gene's absence. This specificity enhances the reliability of experimental results, minimizing any compensatory effects from other pathways or proteins that might occur in less well-defined models.

For researchers and clinicians focusing on GPCR biology, metabolism, or endocrine function, GPR160 knockout cell lines provide an indispensable resource for advancing their studies. Our company offers these expertly developed cell lines, underscoring our commitment to delivering high-quality, innovative tools that empower scientific discovery and enable breakthroughs in the understanding of complex biological systems.

Please note that all services are for research use only. Not intended for any clinical use.

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