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GPM6A Knockout Cell Lines

Gene: GPM6A

Official Full Name: glycoprotein M6Aprovided by HGNC

Gene Summary: Predicted to enable calcium channel activity. Involved in neuron migration and stem cell differentiation. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO37542 GPM6A Knockout cell line (HeLa) Human GPM6A 1:3~1:6 Negative Online Inquiry
KO37543 GPM6A Knockout cell line (HCT 116) Human GPM6A 1:2~1:4 Negative Online Inquiry
KO37544 GPM6A Knockout cell line (HEK293) Human GPM6A 1:3~1:6 Negative Online Inquiry

Background

GPM6A Gene Knockout Cell Lines are specialized cellular models engineered to lack the expression of the GPM6A gene, which plays a significant role in neurodevelopment and synaptic function. By employing CRISPR/Cas9 genome-editing technology, these cell lines are designed to facilitate in-depth studies of GPM6A's biological role and its implications in various neurological disorders.

The key function of GPM6A involves its association with neuronal processes, including influencing cell adhesion, signal transduction, and the regulation of neurotransmitter receptors. Understanding the mechanisms of GPM6A can elucidate its contributions to conditions such as schizophrenia and autism spectrum disorders, providing a cellular basis for examining the gene's impact on neuronal circuitry. These knockout cell lines are indispensable tools for researchers aiming to explore the physiological and pathological functions of GPM6A at both the molecular and cellular levels.

Scientifically, the importance of GPM6A knockout cell lines extends to their diverse applications in preclinical research, drug discovery, and the development of gene therapies. Researchers can utilize these models to assess the effects of pharmacological agents, validate potential therapeutic targets, and investigate the cellular responses to loss of GPM6A function, thereby expanding the potential for breakthroughs in understanding and treating neurodevelopmental conditions.

What sets GPM6A Gene Knockout Cell Lines apart from traditional models is their specificity and the precision of gene-editing techniques used in their development. Unlike general knockout models, these lines offer targeted insights into the role of GPM6A, ensuring highly reproducible and reliable experimental outcomes. This specificity minimizes the risk of off-target effects, enhancing the validity of the research findings.

For researchers and clinicians alike, GPM6A Gene Knockout Cell Lines provide a valuable asset in the quest to uncover the genetic underpinnings of neurological disorders. Their robust nature and relevance in current scientific inquiries make them indispensable for advancing neuroscience research and therapeutic strategies. Our company prides itself on delivering innovative biological products, backed by a dedicated team of scientists and cutting-edge technology, ensuring that researchers have access to the finest tools that support their groundbreaking work.

Please note that all services are for research use only. Not intended for any clinical use.

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