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GORAB Knockout Cell Lines

Gene: GORAB

Official Full Name: golgin, RAB6 interactingprovided by HGNC

Gene Summary: This gene encodes a member of the golgin family, a group of coiled-coil proteins localized to the Golgi. The encoded protein may function in the secretory pathway. The encoded protein, which also localizes to the cytoplasm, was identified by interactions with the N-terminal kinase-like protein, and thus it may function in mitosis. Mutations in this gene have been associated with geroderma osteodysplastica. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2009]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO23154 GORAB Knockout cell line (HeLa) Human GORAB 1:3~1:6 Negative Online Inquiry
KO23155 GORAB Knockout cell line (HCT 116) Human GORAB 1:2~1:4 Negative Online Inquiry
KO23156 GORAB Knockout cell line (HEK293) Human GORAB 1:3~1:6 Negative Online Inquiry
KO23157 GORAB Knockout cell line (A549) Human GORAB 1:3~1:4 Negative Online Inquiry

Background

GORAB Gene Knockout Cell Lines are specialized cellular models engineered to lack the GORAB gene, which encodes a protein known for its role in cellular signaling and the transport of proteins within the cell. These cell lines provide a unique opportunity for researchers to investigate the biological functions associated with the GORAB gene, particularly in relation to disease mechanisms such as developmental disorders and certain forms of cancer. The knockout of this gene allows for the elucidation of its contributions to cellular pathways, enabling researchers to better understand the molecular underpinnings of various physiological and pathological processes.

The key function of GORAB Gene Knockout Cell Lines lies in their ability to serve as a controlled environment for the study of gene function and regulation. By eliminating the expression of the GORAB protein, these cell lines help to reveal compensatory mechanisms and downstream effects that occur in the absence of this gene, providing insights into gene-gene interactions and network modulation within cells. Researchers can apply these models to test hypotheses regarding the GORAB gene's role not only in basic biological processes but also in the development of disease phenotypes.

The scientific importance of GORAB Gene Knockout Cell Lines extends to both fundamental and applied research. In clinical settings, they can be instrumental in drug discovery and development by facilitating the identification of novel therapeutic targets. In research laboratories, they provide a platform for studying gene function, protein interactions, and the effects of gene therapies. Researchers focused on cellular and molecular biology, genetics, and translational medicine find these cell lines particularly valuable for probing the impact of genetic deletions on cell behavior.

Compared to conventional cell lines, GORAB Gene Knockout Cell Lines offer a tailored approach that allows for specific investigations into the functional implications of gene loss, thereby enhancing the robustness of experimental findings. Their availability helps to streamline research processes, enabling faster attainment of results that could lead to novel treatment strategies or biomarker discovery.

Ultimately, the value of GORAB Gene Knockout Cell Lines lies in their versatility as a fundamental tool for both academic and clinical research. They support a deeper understanding of genetic influences on health and disease, equipping researchers and clinicians with the necessary insights to inform their projects or patient care strategies. Our company, with its commitment to providing high-quality biological products, stands at the forefront of genetic research solutions, offering expertise and innovative tools that empower advancements in scientific discovery.

Please note that all services are for research use only. Not intended for any clinical use.

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